Browse our anti-ABCA1 (ABCA1) Antibodies

Full name:
anti-ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 Antibodies (ABCA1)
On www.antibodies-online.com are 182 ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1) Antibodies from 26 different suppliers available. Additionally we are shipping ABCA1 Kits (41) and ABCA1 Proteins (8) and many more products for this protein. A total of 234 ABCA1 products are currently listed.
Synonyms:
ABC-1, Abc1, ABCA1, CERP, HDLDT1, TGD
list all antibodies Gene Name GeneID UniProt
ABCA1 19 O95477
ABCA1 11303 P41233
ABCA1 313210  

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Top referenced anti-ABCA1 Antibodies

  1. Chicken Polyclonal ABCA1 Primary Antibody for ChIP, ELISA - ABIN152883 : Krimbou, Denis, Haidar, Carrier, Marcil, Genest: Molecular interactions between apoE and ABCA1: impact on apoE lipidation. in Journal of lipid research 2004 (PubMed)
    Show all 251 references for 152883

  2. Mouse (Murine) Monoclonal ABCA1 Primary Antibody for IHC (p), WB - ABIN268899 : Zhou, Choi, Li, Xu, Herz: LRP1 controls cPLA2 phosphorylation, ABCA1 expression and cellular cholesterol export. in PLoS ONE 2009 (PubMed)
    Show all 6 references for 268899

  3. Human Monoclonal ABCA1 Primary Antibody for CyTOF, FACS - ABIN4277133 : Wang, Zhang, Chou, Liang, Gu, Ma: Cyclosporine stimulates the renal epithelial sodium channel by elevating cholesterol. in American journal of physiology. Renal physiology 2009 (PubMed)
    Show all 5 references for 4277133

  4. Mouse (Murine) Monoclonal ABCA1 Primary Antibody for FACS - ABIN2477223 : Zarubica, Trompier, Chimini: ABCA1, from pathology to membrane function. in Pflügers Archiv : European journal of physiology 2007 (PubMed)

  5. Human Polyclonal ABCA1 Primary Antibody for FACS, IF (p) - ABIN732188 : Jia, Song, Yang, Ma, Li, Lu, Cao, Zhang, Zhu, Wang, Leng, Cao, Du, Xu: Effects of Tanshinone IIA on the modulation of miR‑33a and the SREBP‑2/Pcsk9 signaling pathway in hyperlipidemic rats. in Molecular medicine reports 2016 (PubMed)

  6. Cow (Bovine) Polyclonal ABCA1 Primary Antibody for WB - ABIN2781512 : Fu, Mukhamedova, Ip, DSouza, Henley, DiTommaso, Kesani, Ditiatkovski, Jones, Lane, Jennings, Smyth, Kile, Sviridov: ABCA12 regulates ABCA1-dependent cholesterol efflux from macrophages and the development of atherosclerosis. in Cell metabolism 2013 (PubMed)

More Antibodies against ABCA1 Interaction Partners

Cow (Bovine) ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1) interaction partners

  1. our results highlight the importance of the LXR (show NR1H3 Antibodies)/ABCA1 system in brain pericytes and suggest a new role for these cells in brain cholesterol homeostasis.

  2. The expression and distribution of the bovine ABCA1 transporter using quantitative PCR and the sequencing of the entire ABCA1 coding region, including the proximal promoter region, are reported.

  3. Aortic endothelial cells transcytose high-density lipoproteins by mechanisms that involve either SR-BI (show SCARB1 Antibodies) or ABCG1 (show ABCG1 Antibodies) but not ABCA1.

Rabbit ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1) interaction partners

  1. CSL112 elevation of ABCA1-dependent efflux may target atherosclerotic plaque for cholesterol removal.

Human ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1) interaction partners

  1. Reduced platelet count, but no major platelet function abnormalities, are associated with loss-of-function ATP-binding cassette-1 gene mutations.

  2. Study report the cryo-EM structure of human ABCA1 with nominal resolutions of 4.1 A for the overall structure and 3.9 A for the massive extracellular domain. The nucleotide-binding domains display a nucleotide-free state, while the two transmembrane domains contact each other through a narrow interface in the intracellular leaflet of the membrane.

  3. ABCB1 (show ABCB1 Antibodies) status is significantly associated with chemo-resistance and poor prognosis in patients with epithelial ovarian cancer

  4. ABCA1 mediates ApoA-I (show APOA1 Antibodies) and ApoA-I (show APOA1 Antibodies) mimetic peptide mobilization of extracellular cholesterol microdomains deposited by macrophages.

  5. EEPD1 is a novel LXR (show NR1H3 Antibodies)-regulated gene in macrophages and that it promotes cellular cholesterol efflux by controlling cellular levels and activity of ABCA1.

  6. This is the first report showing evidence of FTO (show FTO Antibodies) and ABCA1 gene variant interactions affecting BMI, which may explain previously reported population differences

  7. Pim (show PIM1 Antibodies)-1L protects hepatic ABCA1 from lysosomal degradation by facilitating the physical interaction between ABCA1 and liver X receptor beta (show NR1H2 Antibodies) and subsequent stabilization of the ABCA1-Pim (show PIM1 Antibodies)-1L complex and thereby regulates the circulating level of high-density lipoprotein.

  8. High expression of ABCA1 is associated with high carotid intima-media thickness.

  9. Thyrotropin regulated cholesterol content and ABCA1 expression in hepG2 cells.

  10. This meta-analysis provides convincing evidence that polymorphism of ABCA1 R219K is associated with susceptibility to coronary heart disease (CHD (show CHDH Antibodies)) while the CRP (show CRP Antibodies) +1059G/C polymorphism appears to have no correlation with susceptibility to CHD (show CHDH Antibodies).

Mouse (Murine) ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1) interaction partners

  1. apoA-I (show APOA1 Antibodies)/ABCA1-mediated cholesterol efflux without STAT3 (show STAT3 Antibodies) activation can reduce proinflammatory cytokine expression in macrophages.

  2. Our data indicate that a combination of vildagliptin and pravastatin significantly induces the expression of LXR (show NR1H3 Antibodies)-ABCA1/ABCG1 (show ABCG1 Antibodies) cascade and improves cholesterol efflux (P > 0.05) in adipocytes. Our data may explain, at least in part, the improvement in HDL (show HSD11B1 Antibodies)-C levels observed in patients receiving both medications

  3. The findings obtained from apoE (show APOE Antibodies)-/- mice provide epigenetic insights into how EZH2 (show EZH2 Antibodies) increases the risk of atherosclerotic heart disease. One of the pathways by which EZH2 (show EZH2 Antibodies) leads to lipid accumulation and foam cell formation is via epigenetic downregulation of ABCA1 expression.

  4. Overexpressed NHE1 suppresses the expression of ABCA1 protein via increasing the calpain activity in RAW264.7 cells.

  5. Endothelial cholesterol efflux pathways mediated by ABCA1 and ABCG1 (show ABCG1 Antibodies) are nonredundant and atheroprotective, reflecting preservation of endothelial NO synthase (show NOS Antibodies) activity and suppression of endothelial inflammation, especially in regions of disturbed arterial blood flow.

  6. ABCA1 mediates ApoA-I (show APOA1 Antibodies) and ApoA-I (show APOA1 Antibodies) mimetic peptide mobilization of extracellular cholesterol microdomains deposited by macrophages.

  7. ARF6 (show ARF6 Antibodies)-dependent pathway is the predominant route responsible for the ABCA1 internalization and degradation, whereas ARF6 (show ARF6 Antibodies)-independent endocytic pathways may contribute to ABCA1 recycling and efflux of intracellular cholesterol.

  8. EEPD1 is a novel LXR (show NR1H3 Antibodies)-regulated gene in macrophages and that it promotes cellular cholesterol efflux by controlling cellular levels and activity of ABCA1.

  9. Pim (show PIM1 Antibodies)-1L protects hepatic ABCA1 from lysosomal degradation by facilitating the physical interaction between ABCA1 and liver X receptor beta (show NR1H2 Antibodies) and subsequent stabilization of the ABCA1-Pim (show PIM1 Antibodies)-1L complex and thereby regulates the circulating level of high-density lipoprotein.

  10. Nucleolin (show NCL Antibodies) protects macrophages from oxLDL-induced foam cell formation in hyperlipidemia through up-regulating ABCA1 expression.

Pig (Porcine) ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1) interaction partners

  1. ABCA1 promoter variants affect transcription activity and plasma HDL (show HSD11B1 Antibodies) level in pigs

  2. ABCA1 was up-regulated in monocytes of hypercholesterolemic pigs via oxidized-LDL and prior to development coronary atherosclerosis.

  3. Both region-specific and ubiquitous (ABCA1) phenotype changes were identified as early prelesional responses of the endothelium to hypercholesterolemia

ABCA1 Antigen Profile

Antigen Summary

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in this gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency.

Alternative names and synonyms associated with ABCA1

  • ATP-binding cassette, sub-family A (ABC1), member 1 (ABCA1) antibody
  • ATP-binding cassette, sub-family A (ABC1), member 1 (abca1) antibody
  • ATP-binding cassette, sub-family A (ABC1), member 1 (Abca1) antibody
  • ATP-binding cassette, subfamily A (ABC1), member 1 (Abca1) antibody
  • ABC-1 antibody
  • Abc1 antibody
  • ABCA1 antibody
  • CERP antibody
  • HDLDT1 antibody
  • TGD antibody

Protein level used designations for ABCA1

ATP-binding cassette, sub-family A member 1 , ATP-binding cassette transporter 1 , Cholesterol efflux regulatory protein , ATP-binding cassette sub-family A member 1 , ATP-binding cassette transporter , ATP-binding cassette, sub-family A (ABC1), member 1 , ATP-binding cassette, sub-family A member 1-like , ATP-binding cassette sub-family A member 1-like , ATP-binding cassette transporter A1 , cholesterol efflux regulatory protein , membrane-bound , ATP-binding cassette 1

GENE ID SPECIES
464630 Pan troglodytes
535379 Bos taurus
100013781 Monodelphis domestica
100356765 Oryctolagus cuniculus
100441342 Pongo abelii
100483394 Ailuropoda melanoleuca
100491942 Xenopus (Silurana) tropicalis
716107 Macaca mulatta
100557081 Anolis carolinensis
373945 Gallus gallus
19 Homo sapiens
11303 Mus musculus
481651 Canis lupus familiaris
100152112 Sus scrofa
313210 Rattus norvegicus
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