ABCA1 antibody (AA 1100-1300)

Catalog No. ABIN540803

Product Details anti-ABCA1 Antibody

Target: ABCA1 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1))

Binding Specificity: AA 1100-1300

Reactivity: Mouse, Human, Rat, Hamster

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABCA1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of ABCA1.

Specificity: This antibody is specific to ABCA1.

Cross-Reactivity: Hamster, Human, Mouse, Rat

Characteristics: Antibody Reactive Against Synthetic Peptide.

Immunogen: A synthetic peptide corresponding to amino acids 1100-1300 of human ABCA1.

Application Details

Application Notes: Flow Cytometry (1:400)
Immunocytochemistry (1:100)
Immunofluorescence (1:100)
Immunohistochemistry (1:200)
Immunoprecipitation (1:10-1:500)
Western Blot (1:500)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.05 % sodium azide).

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-ABCA1 antibody (ABIN540803)

Nakanishi, Vikstedt, Söderlund, Lee-Rueckert, Hiukka, Ehnholm, Muilu, Metso, Naukkarinen, Palotie, Kovanen, Jauhiainen, Taskinen: "Serum, but not monocyte macrophage foam cells derived from low HDL-C subjects, displays reduced cholesterol efflux capacity." in: Journal of lipid research, Vol. 50, Issue 2, pp. 183-92, (2009) (PubMed).

Nandi, Ma, Denis, Karwatsky, Li, Jiang, Zha: "ABCA1-mediated cholesterol efflux generates microparticles in addition to HDL through processes governed by membrane rigidity." in: Journal of lipid research, Vol. 50, Issue 3, pp. 456-66, (2009) (PubMed).

Dang, Liu, Pang, Li, Wang, Shyy, Zhu: "Suppression of 2,3-oxidosqualene cyclase by high fat diet contributes to liver X receptor-alpha-mediated improvement of hepatic lipid profile." in: The Journal of biological chemistry, Vol. 284, Issue 10, pp. 6218-26, (2009) (PubMed).

Bhatnagar, Damron, Hillgartner: "Fibroblast growth factor-19, a novel factor that inhibits hepatic fatty acid synthesis." in: The Journal of biological chemistry, Vol. 284, Issue 15, pp. 10023-33, (2009) (PubMed).

Henry-Berger, Mouzat, Baron, Bernabeu, Marceau, Saru, Sapin, Lobaccaro, Caira: "Endoglin (CD105) expression is regulated by the liver X receptor alpha (NR1H3) in human trophoblast cell line JAR." in: Biology of reproduction, Vol. 78, Issue 6, pp. 968-75, (2008) (PubMed).

Target Details for ABCA1

Target: ABCA1 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1))

Alternative Name: ABCA1 (ABCA1 Products)

Synonyms: ABC-1 antibody, ABC1 antibody, CERP antibody, HDLDT1 antibody, TGD antibody, ABCA1 antibody, Abc1 antibody, ATP-binding cassette A1 antibody, Arabidopsis thaliana ATP-binding cassette A1 antibody, AtABCA1 antibody, im:7136239 antibody, sb:cb407 antibody, wu:fa07e06 antibody, zgc:171581 antibody, ATP binding cassette subfamily A member 1 antibody, ATP-binding cassette, sub-family A (ABC1), member 1 antibody, ATP-binding cassette A1 antibody, ATP-binding cassette, sub-family A (ABC1), member 1B antibody, ABCA1 antibody, Abca1 antibody, abca1 antibody, abca1b antibody

Gene ID: 19

Pathways: Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism