Browse our anti-Defensin, alpha 6, Paneth Cell-Specific (DEFA6) Antibodies

Full name:
anti-Defensin, alpha 6, Paneth Cell-Specific Antibodies (DEFA6)
On www.antibodies-online.com are 31 Defensin, alpha 6, Paneth Cell-Specific (DEFA6) Antibodies from 8 different suppliers available. Additionally we are shipping Defensin, alpha 6, Paneth Cell-Specific Kits (8) and Defensin, alpha 6, Paneth Cell-Specific Proteins (3) and many more products for this protein. A total of 44 Defensin, alpha 6, Paneth Cell-Specific products are currently listed.
Synonyms:
DEF6, DEFA6, Defcr6, HD-6
list all antibodies Gene Name GeneID UniProt
DEFA6 613223  
DEFA6 1671 Q01524
DEFA6 13240 P50704

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Top referenced anti-Defensin, alpha 6, Paneth Cell-Specific Antibodies

  1. Human Polyclonal DEFA6 Primary Antibody for IHC, IHC (p) - ABIN4304790 : Granlund, Beisvag, Torp, Flatberg, Kleveland, Ostvik, Waldum, Sandvik: Activation of REG family proteins in colitis. in Scandinavian journal of gastroenterology 2011 (PubMed)
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More Antibodies against Defensin, alpha 6, Paneth Cell-Specific Interaction Partners

Human Defensin, alpha 6, Paneth Cell-Specific (DEFA6) interaction partners

  1. alpha-Defensin 6 Self-Assembly Prevents Adhesion and Suppresses Virulence Traits of Candida albicans

  2. Downregulation of HD6 in noninflamed mucosa may contribute to mucosal barrier dysfunction of patients with Crohn's Disease.

  3. Paneth cell alpha-defensin 6 is an antimicrobial peptide (show cAMP Antibodies).

  4. Native HD-6 readily self-assembles into elongated fibrils observable by transmission electron microscopy, agglutinates both Gram-negative and -positive bacteria, and prevents the Listeria monocytogenes from invading cultured cells.

  5. Authors show that although NOD2 (show NOD2 Antibodies) by itself can slightly up-regulate expression of HD5 (show DEFA5 Antibodies) and HD6, it can strongly down-regulates their expression during differentiation of the Paneth cell lineage mainly by inhibiting activation of the MAPK (show MAPK1 Antibodies) pathway.

  6. In the meta-analysis, DEFA6 rs13275170 and DEFB1 (show DEFB1 Antibodies) rs2738169 had both a 1.3-fold increased odds ratio for gastric cancer.

  7. study reports that HD6 affords protection against invasion by enteric bacterial pathogens in vitro and in vivo; after stochastic binding to bacterial surface proteins, HD6 undergoes ordered self-assembly to form fibrils and nanonets that surround and entangle bacteria

  8. Defensin alpha 6 (DEFA 6) may have a role in adenoma but not in progression to colon carcinoma

  9. defensin (show DEF Antibodies) alpha6 is highly expressed in colon cancer cell lines

  10. Crystal structure of HD6.

Defensin, alpha 6, Paneth Cell-Specific (DEFA6) Antigen Profile

Antigen Summary

Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 6, is highly expressed in the secretory granules of Paneth cells of the small intestine, and likely plays a role in host defense of human bowel.

Alternative names and synonyms associated with Defensin, alpha 6, Paneth Cell-Specific (DEFA6)

  • defensin, alpha 6, Paneth cell-specific (DEFA6) antibody
  • defensin alpha 6 (Defa6) antibody
  • defensin, alpha 6 (DEFA6) antibody
  • defensin, alpha, 6 (Defa6) antibody
  • DEF6 antibody
  • DEFA6 antibody
  • Defcr6 antibody
  • HD-6 antibody

Protein level used designations for DEFA6

defensin, alpha 6, Paneth cell-specific , alpha-defensin 6, Paneth cell-specific , Paneth cell-specific alpha-defensin 6 , alpha-defensin 6 , defensin-6 , defensin 6 , alpha-defensin 6/12 , alpha-defensin, 6 , cryptdin-2 , defensin related cryptdin 6 , defensin-related cryptdin-6/12

GENE ID SPECIES
717000 Macaca mulatta
100307029 Equus caballus
613223 Rattus norvegicus
619354 Pan troglodytes
1671 Homo sapiens
13240 Mus musculus
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