Browse our anti-Zinc Finger Protein 163 (ZNF163) Antibodies

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anti-Zinc Finger Protein 163 Antibodies (ZNF163)
On are 60 Zinc Finger Protein 163 (ZNF163) Antibodies from 19 different suppliers available. Additionally we are shipping Zinc Finger Protein 163 Proteins (7) and many more products for this protein. A total of 69 Zinc Finger Protein 163 products are currently listed.
AW495828, GFI-1, GFI1A, Pal-1, Pal1, SCN2, ZNF163
list all antibodies Gene Name GeneID UniProt
ZNF163 14581 P70338
ZNF163 2672 Q99684
ZNF163 24388 Q07120

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Top referenced anti-Zinc Finger Protein 163 Antibodies

  1. Human Monoclonal ZNF163 Primary Antibody for IF, WB - ABIN394301 : Alcina, Fernández, Gonzalez, Catalá-Rabasa, Fedetz, Ndagire, Leyva, Guerrero, Arnal, Delgado, Lucas, Izquierdo, Matesanz: Tag-SNP analysis of the GFI1-EVI5-RPL5-FAM69 risk locus for multiple sclerosis. in European journal of human genetics : EJHG 2010 (PubMed)
    Show all 5 references for 394301

  2. Human Monoclonal ZNF163 Primary Antibody for ELISA, WB - ABIN969174 : Dwivedi, Anderson, Tilley, May, Morris: Role of oncoprotein growth factor independent-1 (GFI1) in repression of 25-hydroxyvitamin D 1alpha-hydroxylase (CYP27B1): a comparative analysis in human prostate cancer and kidney cells. in The Journal of steroid biochemistry and molecular biology 2007 (PubMed)
    Show all 2 references for 969174

  3. Human Monoclonal ZNF163 Primary Antibody for EIA, WB - ABIN1109563 : Kimura, Wakamatsu, Suzuki, Ota, Nishikawa, Yamashita, Yamamoto, Sekine, Tsuritani, Wakaguri, Ishii, Sugiyama, Saito, Isono, Irie, Kushida, Yoneyama, Otsuka, Kanda, Yokoi, Kondo, Wagatsuma, Murakawa et al.: Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. ... in Genome research 2006 (PubMed)

  4. Cow (Bovine) Polyclonal ZNF163 Primary Antibody for WB - ABIN2779720 : Doan, Porter, Duan, Flubacher, Montoya, Tsichlis, Horwitz, Gilks, Grimes: Targeted transcriptional repression of Gfi1 by GFI1 and GFI1B in lymphoid cells. in Nucleic acids research 2004 (PubMed)

  5. Cow (Bovine) Polyclonal ZNF163 Primary Antibody for WB - ABIN2777468 : Duan, Zarebski, Montoya-Durango, Grimes, Horwitz: Gfi1 coordinates epigenetic repression of p21Cip/WAF1 by recruitment of histone lysine methyltransferase G9a and histone deacetylase 1. in Molecular and cellular biology 2005 (PubMed)

More Antibodies against Zinc Finger Protein 163 Interaction Partners

Mouse (Murine) Zinc Finger Protein 163 (ZNF163) interaction partners

  1. If Gfi1 levels fall below a threshold, Id1 (show ID1 Antibodies) expression increases and renders E2A (show TCF3 Antibodies) unable to function, which prevents hematopoietic progenitors from engaging along the B lymphoid lineage

  2. These results clearly demonstrate that Gfi1 is a critical transcriptional regulator that controls the development of CD4pos and NK1.1pos Invariant natural killer T cells.

  3. this study demonstrates the critical role of Gfi1 in the regulation of myeloid cells, and prevention of spontaneous lupus autoimmunity by negatively controlling TLR7 (show TLR7 Antibodies) signaling

  4. these findings demonstrate a novel regulatory role of Gfi1 in the regulation of the Th1 (show HAND1 Antibodies)-type immune response.

  5. GFI1 proteins recruit the chromatin-modifying protein LSD1 (show KDM1A Antibodies), a member of the CoREST (show Rcor2 Antibodies) repressive complex, to epigenetically silence the endothelial program in haemogenic endothelium and allow the emergence of blood cells

  6. GFI1 inhibits NLRP3 (show NLRP3 Antibodies) inflammasome activation and IL-1beta (show IL1B Antibodies) secretion in macrophages

  7. Gfi-1 is linked to the erythroid gene regulatory network by repressing Id2 expression.

  8. results, supported by evidence from mouse models, identify GFI1 and GFI1B (show GFI1B Antibodies) as prominent medulloblastoma oncogenes and implicate 'enhancer hijacking' as an efficient mechanism driving oncogene (show RAB1A Antibodies) activation in a childhood cancer

  9. Gfi1 and gfi1b (show GFI1B Antibodies) repress rag transcription in plasmacytoid dendritic cells in vitro.

  10. Our data indicate that Gfi1 is required for hematopoietic precursors to withstand Notch1 (show NOTCH1 Antibodies) activation and to maintain Notch1 (show NOTCH1 Antibodies) dependent transcriptional programming to determine early T-lymphoid lineage identity.

Human Zinc Finger Protein 163 (ZNF163) interaction partners

  1. Simvastatin attenuates the tumor-associated macrophage mediated gemcitabine resistance of PDAC by blocking the TGF-beta1/Gfi-1 axis.

  2. combination of the sequence-specific and nonspecific DNA-binding modes of SATB1 (show SATB1 Antibodies) should be advantageous in a search for target loci during transcriptional regulation

  3. GFI1(36S) homozygous patients exhibited a sustained response to treatment with hypomethylating agents, whereas GFI1(36N) patients had a poor sustained response to this therapy. Because allele status of GFI1(36N) is readily determined using basic molecular techniques, we propose inclusion of GFI1(36N) status in future prospective studies for MDS (show PAFAH1B1 Antibodies) patients to better predict prognosis and guide therapeutic decisions.

  4. Maternal-smoking sensitive CpG sites in newborns were significantly associated with cg18146737 SNP located proximal to GFI1.

  5. In this study, the influence of prenatal smoking exposure on the childrens' DNA methylation (show HELLS Antibodies) state of a CpG island located upstream of the promoter of the growth factor independent 1 (GFI1) gene was analyzed. Significant hypomethylation was observed in this CpG island in SIDS (show IDS Antibodies) cases with cigarette smoke exposure compared to non-exposed cases.

  6. Gfi1 gene expression is regulated by cytokines in activated T cells.

  7. miR-495 directly interacts with the Gfi1 3'UTR to regulate Gfi1 at a post-transcriptional level and the expression level of miR-495 is inversely correlated with the Gfi1 protein level in medulloblastoma specimens.

  8. Gfi1 acts as a transcriptional repressor by recruiting histone-modifying enzymes to promoters and enhancers of target genes. Mutations of the C-terminal zinc finger domain causes congenital neutropenia. It may be involved in leukemia and lymphoma. Review.

  9. During infection, the incoming HCMV rapidly downregulates the GFI1 mRNA and protein in both wild-type cells and in cells in which EZH2 (show EZH2 Antibodies), NDY1/KDM2B (show KDM2B Antibodies) or JARID2 (show JARID2 Antibodies) were knocked down.

  10. Data shows that MYB regulates the expression of endogenous human GFI1.

Zinc Finger Protein 163 (ZNF163) Antigen Profile

Antigen Summary

This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene.

Alternative names and synonyms associated with Zinc Finger Protein 163 (ZNF163)

  • growth factor independent 1 (Gfi1) antibody
  • growth factor independent 1 transcription repressor (GFI1) antibody
  • growth factor independent 1 transcription repressor (Gfi1) antibody
  • AW495828 antibody
  • GFI-1 antibody
  • GFI1A antibody
  • Pal-1 antibody
  • Pal1 antibody
  • SCN2 antibody
  • ZNF163 antibody

Protein level used designations for ZNF163

growth factor independent protein 1 , zinc finger protein Gfi-1 , growth factor independence-1 , zinc finger protein 163 , growth factor independence 1 , Growth factor independent-1

14581 Mus musculus
2672 Homo sapiens
490156 Canis lupus familiaris
24388 Rattus norvegicus
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