GFI1B antibody (N-Term)

Catalog No. ABIN2779273

Product Details anti-GFI1B Antibody

Target: GFI1B (Growth Factor Independent 1B Transcription Repressor (GFI1B))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Goat, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GFI1B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: MPRSFLVKSK MAHTYHQPRV QEDEPLWPPA LTPVPRDQAP SNSPVLSTLF

Predicted Reactivity: Cow: 83%, Dog: 100%, Goat: 83%, Horse: 100%, Human: 100%, Mouse: 83%, Pig: 93%, Rat: 82%

Characteristics: This is a rabbit polyclonal antibody against GFI1B. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GFI1B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 330 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GFI1B

Target: GFI1B (Growth Factor Independent 1B Transcription Repressor (GFI1B))

Alternative Name: GFI1B (GFI1B Products)

Synonyms: GFI1B antibody, GFI antibody, znf544 antibody, MGC80648 antibody, Gfi-1B antibody, growth factor independent 1B transcriptional repressor antibody, growth factor independent 1B transcription repressor L homeolog antibody, Zinc finger protein Gfi-1b antibody, growth factor independent 1B antibody, GFI1B antibody, Gfi1b antibody, gfi1b.L antibody, gfi1b antibody

Background: GFI1B acts in the late stage of erythroid differentiation as a transcriptional repressor. GATA-1 and NF-Y both contribute to erythroid-specific transcriptional activation of the Gfi-1B promoter. This zinc finger protein mediates erythroid expansion and has a role in normal erythropoiesis.
Protein Interaction Partner: ZNRD1, EFEMP2, NSMF, IFFO1, RCHY1, TENC1, HECW1, MID2, CCDC85B, COPS5, RUNDC3A, PDLIM5, FBLN5, MATR3, PDE4DIP, BRE, PICK1, HGS, DNAJA3, KALRN, BECN1, LTBP4, VSNL1, TRIP6, TRAF1, TMF1, TAF1, ATXN2, TRIM27, PSMA3, NOTCH1, NELL2, NELL1, LAMB1, JAG2, HSPG2, H
Protein Size: 330

Molecular Weight: 38 kDa

Gene ID: 8328

NCBI Accession: NM_004188, NP_004179

UniProt: Q5VTD9

Pathways: Cellular Response to Molecule of Bacterial Origin