Browse our BRD2 Proteins (BRD2)

Full name:
Bromodomain Containing 2 Proteins (BRD2)
On are 13 Bromodomain Containing 2 (BRD2) Proteins from 5 different suppliers available. Additionally we are shipping BRD2 Antibodies (75) and BRD2 Kits (1) and many more products for this protein. A total of 95 BRD2 products are currently listed.
AW228947, brd2, brd2-a, D6S113E, D17H6S113E, fe47f02, fi85h05, Frg-1, fsh, Fsrg-1, fsrg1, mKIAA4005, nat, ring3, rnf3, wu:fe47f02, wu:fi85h05
list all proteins Gene Name GeneID UniProt
BRD2 6046 P25440
BRD2 14312 Q7JJ13
BRD2 294276 Q6MGA9

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BRD2 Proteins (BRD2) by Origin

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More Proteins for BRD2 Interaction Partners

Human Bromodomain Containing 2 (BRD2) interaction partners

  1. The identification of RNF43 (show RNF43 Proteins) mutations in a distinct subset of intraductal papillary neoplasm of the bile ducts revealed a new molecular role in the pathogenesis of this disease

  2. LRP1B (show LRP1B Proteins), BRD2 and CACNA1D (show CACNA1D Proteins) are new candidate genes in fetal metabolic programming of newborns exposed to maternal hyperglycemia.

  3. This study implicates BET Brds as important regulators of IkappaB kinase (show CHUK Proteins)/NF-kappaB (show NFKB1 Proteins)-mediated synovial inflammation of RA and identifies BET proteins as novel therapeutic targets in inflammatory arthritis.

  4. An unexpected role for the bromodomain and extraterminal domain (BET) proteins BRD2 and BRD4 (show BRD4 Proteins) in maintaining oncogenic IKK (show CHUK Proteins) activity in activated B-cell-like diffuse large B-cell lymphoma.

  5. BET proteins, particularly Brd2 and Brd4 (show BRD4 Proteins), may play a key role in the regulation of Nrf2 (show GABPA Proteins)-dependent antioxidant gene transcription and are hence an important target for augmenting antioxidant responses in oxidative stress-mediated diseases.

  6. The C-terminal domain of Brd2 is important for chromatin interaction and regulation of transcription and alternative splicing.

  7. A structural basis for BRD2/4-mediated host chromatin interaction and oligomer assembly of Kaposi sarcoma-associated herpesvirus and murine gammaherpesvirus LANA proteins.

  8. The SNP alleles in BRD2, Cx-36 (show GJD2 Proteins), and ME2 and microdeletions in 15q13.3, 15q11.2, and 16p13.11 also contribute risk to juvenile myoclonic epilepsy'

  9. BRD2, BRD3 (show BRD3 Proteins), and BRD4 (show BRD4 Proteins) interact with gammaretroviral INs (show INS Proteins) and serve as cofactors for murine leukemia virus integration.

  10. our results identify BRD2 as a new Tat (show TAT Proteins)-independent suppressor of HIV transcription in latently infected cells and underscore the therapeutic potential of BET inhibitors in the reversal of HIV latency.

Mouse (Murine) Bromodomain Containing 2 (BRD2) interaction partners

  1. BRD2 acts to augment the boundary function of CTCF (show CTCF Proteins) both by limiting the spread or range of enhancer activity and by physically preventing the formation of cross-boundary contacts genome-wide.

  2. Brd2 and Brd4 (show BRD4 Proteins) genetic transcription required for Th17 cell development and adaptive immunity.

  3. This study reveals an antagonistic relationship between H2A.Z (show H2AFZ Proteins).1ub and BRD2 to regulate the transcriptional balance at bivalent genes to enable proper execution of developmental programs.

  4. BRD2 is involved in the modulation of neuroinflammatory responses through PAI-1 (show SERPINE1 Proteins) and via the regulation of epigenetic reader BET protein

  5. DNA demethylation of the Brd2 promoter region induced Brd2 expression during differentiation of 3T3-L1 cells into adipocytes.

  6. Brd2 inhibits adipogenesis via the ERK1/2 signaling pathway in 3T3-L1 adipocytes.

  7. A structural basis for BRD2/4-mediated host chromatin interaction and oligomer assembly of Kaposi sarcoma-associated herpesvirus and murine gammaherpesvirus LANA proteins.

  8. We conclude that Brd2 plays a critical, independent role in regulation of mitogenic response genes

  9. Data show that infection of macrophages with Listeria monocytogenes caused binding of the BET proteins Brd2, Brd3, and, most prominently, Brd4 to the Nos2 promoter.

  10. Identification of motif B of Brd2 as a dimerization domain involved in association to mitotic chromosomes and proper recognition of acetylated chromatin.

Zebrafish Bromodomain Containing 2 (BRD2) interaction partners

  1. brd2a on chromosome 19 exhibits both maternal and zygotic contributions to early development and patterning, analogous to the brd2 ortholog in Drosophila.

BRD2 Protein Profile

Protein Summary

This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene.

Alternative names and synonyms associated with BRD2

  • Ring3 protein (CHLREDRAFT_190116)
  • Ring3 protein (CHLREDRAFT_150233)
  • Ring3 protein (CHLREDRAFT_182576)
  • Ring3 protein (CHLREDRAFT_188250)
  • bromodomain containing 2 (BRD2)
  • bromodomain containing 2 (Brd2)
  • bromodomain containing 2 (brd2)
  • bromodomain-containing 2a (brd2a)
  • AW228947 protein
  • brd2 protein
  • brd2-a protein
  • D6S113E protein
  • D17H6S113E protein
  • fe47f02 protein
  • fi85h05 protein
  • Frg-1 protein
  • fsh protein
  • Fsrg-1 protein
  • fsrg1 protein
  • mKIAA4005 protein
  • nat protein
  • ring3 protein
  • rnf3 protein
  • wu:fe47f02 protein
  • wu:fi85h05 protein

Protein level used designations for BRD2

Ring3 protein , O27.1.1 , bromodomain-containing 2 , bromodomain-containing protein 2 , female sterile homeotic-related gene 1 , really interesting new gene 3 protein , collagen type XI alpha 2 , glutamate-cysteine ligase catalytic subunit , ring finger protein 3

5715712 Chlamydomonas reinhardtii
5721686 Chlamydomonas reinhardtii
5724100 Chlamydomonas reinhardtii
5728991 Chlamydomonas reinhardtii
6046 Homo sapiens
417049 Gallus gallus
474868 Canis lupus familiaris
100141307 Sus scrofa
505358 Bos taurus
14312 Mus musculus
294276 Rattus norvegicus
394399 Xenopus laevis
30445 Danio rerio
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