Browse our anti-TFAM (TFAM) Antibodies

Full name:
anti-Transcription Factor A, Mitochondrial Antibodies (TFAM)
On are 145 Transcription Factor A, Mitochondrial (TFAM) Antibodies from 24 different suppliers available. Additionally we are shipping TFAM Proteins (13) and TFAM Kits (10) and many more products for this protein. A total of 181 TFAM products are currently listed.
AI661103, Hmgts, MGC153358, MTTF1, Mttfa, mttfa-A, TCF6, TCF6L1, TCF6L2, TCF6L3, tsHMG, xl-mtTFA, zgc:153358

Most Popular Reactivities for anti-TFAM (TFAM) Antibodies

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anti-Human TFAM Antibodies:

anti-Mouse (Murine) TFAM Antibodies:

anti-Rat (Rattus) TFAM Antibodies:

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Top referenced anti-TFAM Antibodies

  1. Cow (Bovine) Polyclonal TFAM Primary Antibody for WB - ABIN2777277 : Shi, Burkart, Nicoloro, Czech, Straubhaar, Corvera: Paradoxical effect of mitochondrial respiratory chain impairment on insulin signaling and glucose transport in adipose cells. in The Journal of biological chemistry 2008 (PubMed)
    Show all 10 references for 2777277

  2. Human Monoclonal TFAM Primary Antibody for ICC, IF - ABIN4336018 : Morris, Meers, Booth, Fritsche, Hardin, Thyfault, Ibdah: PGC-1α overexpression results in increased hepatic fatty acid oxidation with reduced triacylglycerol accumulation and secretion. in American journal of physiology. Gastrointestinal and liver physiology 2012 (PubMed)
    Show all 3 references for 4336018

  3. Human Polyclonal TFAM Primary Antibody for IF, IHC - ABIN1533816 : Parisi, Clayton: Similarity of human mitochondrial transcription factor 1 to high mobility group proteins. in Science (New York, N.Y.) 1991 (PubMed)

  4. Mouse (Murine) Polyclonal TFAM Primary Antibody for WB - ABIN2779902 : Noack, Bednarek, Heidler, Ladig, Holtz, Szibor: TFAM-dependent and independent dynamics of mtDNA levels in C2C12 myoblasts caused by redox stress. in Biochimica et biophysica acta 2006 (PubMed)

  5. Rat (Rattus) Polyclonal TFAM Primary Antibody for WB - ABIN411602 : Arduini, Serviddio, Escobar, Tormos, Bellanti, Viña, Monsalve, Sastre: Mitochondrial biogenesis fails in secondary biliary cirrhosis in rats leading to mitochondrial DNA depletion and deletions. in American journal of physiology. Gastrointestinal and liver physiology 2011 (PubMed)

  6. Human Polyclonal TFAM Primary Antibody for FACS, IF - ABIN654229 : Shulman, Chibnik, Aubin, Schneider, Bennett, De Jager: Intermediate phenotypes identify divergent pathways to Alzheimer's disease. in PLoS ONE 2010 (PubMed)

More Antibodies against TFAM Interaction Partners

Human Transcription Factor A, Mitochondrial (TFAM) interaction partners

  1. In vivo, AICAR (show ATIC Antibodies) significantly reduced osteosarcoma growth without apparent body weight loss and AICAR (show ATIC Antibodies) increased both mitochondrial proliferation and apoptotic activity in treated tumor tissues. AICAR (show ATIC Antibodies) showed anticancer effects in osteosarcoma cells through an AMPK (show PRKAA1 Antibodies)-dependent peroxisome proliferatoractivated receptor-gamma coactivator-1alpha (PGC-1alpha (show PPARGC1A Antibodies))/mitochondrial transcription factor A (TFAM)/mitochondrial pathway

  2. the present study identified the interaction of miR (show MLXIP Antibodies)-590-3p and TFAM in colon cancer. TFAM was identified as a target of miR (show MLXIP Antibodies)-590-3p, and miR (show MLXIP Antibodies)-590-3p enhanced the proliferation of SW480 cells.

  3. The results of the present study provided evidence that resistance to cisplatin chemotherapy in ERpositive breast cancer may be through TFAM and indicated that TFAM may be a target for chemoresistance in patients with breast cancer.

  4. miR (show MLXIP Antibodies)-199a-3p is able to attenuate cisplatin resistance in breast cancer cells through inhibiting TFAM expression.

  5. We conducted a meta-analysis of studies involving CHAT, TFAM, and VR22 (show CTNNA3 Antibodies) polymorphisms and Alzheimer disease susceptibility. For TFAM and VR22 (show CTNNA3 Antibodies), no significant association was detected in studied single-nucleotide polymorphisms (SNPs).Rs1937 and rs2306604 of TFAM, are not significantly associated with AD risk.

  6. Results showed that TFAM formed oligomers in mitochondria by in situ chemical cross-linking and suggested the importance of the dimerization of TFAM molecules in the distribution of mtDNA in cells.

  7. Report failed upregulation of TFAM protein and mitochondrial DNA in oxidatively deficient fibers in skeletal muscle of chronic obstructive pulmonary disease patients.

  8. Data show that mtTFA proteins are highly expressed in cancer and drug-resistant cells compared to normal cells, and the mtTFA expression is upregulated by signals of oxidative and DNA damage stress in cancer cells. [review]

  9. TFAM overexpression suppressed mitoROS and their upregulation in rat cardiomyocytes.

  10. TFAM dimerization enhances mitochondrial DNA compaction by promoting looping of the DNA.

Pig (Porcine) Transcription Factor A, Mitochondrial (TFAM) interaction partners

  1. TFAM may exert a critical role in porcine gametogenesis and preimplantation embryo development.

Cow (Bovine) Transcription Factor A, Mitochondrial (TFAM) interaction partners

  1. Our results suggest that TFAM plays an important role in lipid metabolism and may be a strong candidate gene for obesity in mammals.

  2. de novo mtTFA expression associated with mitochondrial biogenesis activation & high levels of nuclear respiratory factor-1 (show NRF1 Antibodies) mRNA from oocyte stage onwards argue for essential function of these factors during the first steps of bovine embryogenesis.

Mouse (Murine) Transcription Factor A, Mitochondrial (TFAM) interaction partners

  1. Perturbation of mitochondrial complex function by ablation of the mitochondrial transcription factor A (Tfam) reproduces multiple hallmarks of aging in hippocampal neurogenesis.

  2. During muscle differentiation, Tfam protein levels are regulated by the availability of Tfam mRNA, which is controlled by both transcription and mRNA stability.

  3. TFAM binds to RNA-containing 4-way junctions but does not bind appreciably to RNA hairpins, internal loops, or linear RNA:DNA hybrids.

  4. Data show that mitochondrial transcription factor A (TFAM) packages single mitochondrial DNA (mtDNA) molecules.

  5. There was upregulation of mtDNA and TFAM in 6-wk diabetic mice, suggesting that TFAM activation could be a therapeutic strategy to treat peripheral neuropathy.

  6. This study demonistrated that Tfam gene inactive patkinsin disease cause dopamine loss and circadian rhythm disorder.

  7. Mitochondrial transcription factor A, an endogenous danger signal, promotes TNFalpha (show TNF Antibodies) release via RAGE (show AGER Antibodies)- and TLR9 (show TLR9 Antibodies)-responsive plasmacytoid dendritic cells.

  8. overexpression of TFAM can restore mitochondrial function to normal levels in NYGGF4 (show PID1 Antibodies)-overexpressing adipocytes

  9. Acute exercise induces tumour suppressor protein p53 (show TP53 Antibodies) translocation to the mitochondria and promotes a p53 (show TP53 Antibodies)-Tfam-mitochondrial DNA complex in skeletal muscle.

  10. Data indicate that TFAM-deficient keratinocytes failed to generate mitochondria-derived reactive oxygen species, and prevented the transmission of Notch (show NOTCH1 Antibodies) and beta-catenin (show CTNNB1 Antibodies) signals for epidermal differentiation and hair follicle development.

TFAM Antigen Profile

Antigen Summary

This gene encodes a key mitochondrial transcription factor containing two high mobility group motifs. The encoded protein also functions in mitochondrial DNA replication and repair. Sequence polymorphisms in this gene are associated with Alzheimer's and Parkinson's diseases. There are pseudogenes for this gene on chromosomes 6, 7, and 11. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with TFAM

  • transcription factor A, mitochondrial (TFAM) antibody
  • transcription factor A, mitochondrial (tfam) antibody
  • transcription factor A, mitochondrial (Tfam) antibody
  • AI661103 antibody
  • Hmgts antibody
  • MGC153358 antibody
  • MTTF1 antibody
  • Mttfa antibody
  • mttfa-A antibody
  • TCF6 antibody
  • TCF6L1 antibody
  • TCF6L2 antibody
  • TCF6L3 antibody
  • tsHMG antibody
  • xl-mtTFA antibody
  • zgc:153358 antibody

Protein level used designations for TFAM

transcription factor A, mitochondrial , HMG box mitochondrial transcription factor , mitochondrial transcription factor 1 , mitochondrial transcription factor A , transcription factor 6 , transcription factor 6-like 1 , transcription factor 6-like 2 (mitochondrial transcription factor) , transcription factor 6-like 3 , mtTFA , transcription factor 6-like 2 , TS-HMG , testis-specific HMG-box protein m-tsHMG , testis-specific high mobility group protein

373888 Gallus gallus
394385 Xenopus laevis
571106 Danio rerio
7019 Homo sapiens
488989 Canis lupus familiaris
397279 Sus scrofa
510059 Bos taurus
21780 Mus musculus
83474 Rattus norvegicus
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