Browse our C1QA Proteins (C1QA)

Full name:
Complement Component 1, Q Subcomponent, A Chain Proteins (C1QA)
On www.antibodies-online.com are 20 Complement Component 1, Q Subcomponent, A Chain (C1QA) Proteins from 5 different suppliers available. Additionally we are shipping C1QA Antibodies (67) and C1QA Kits (26) and many more products for this protein. A total of 121 C1QA products are currently listed.
Synonyms:
AI255395, C1q, C1QA, zgc:109903
list all proteins Gene Name GeneID UniProt
C1QA 712 P02745
C1QA 298566 P31720
C1QA 12259 P98086

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C1QA Proteins (C1QA) by Origin

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More Proteins for C1QA Interaction Partners

Zebrafish Complement Component 1, Q Subcomponent, A Chain (C1QA) interaction partners

  1. the overall architecture of Dare-C1qAgD is similar to human C1qA, residues involved in C1qBgD, C1qCgD, and CRP (show CRP Proteins) binding are somewhat different while residues involved in IgG binding are not present in zebrafish. The structure gives insight into how human and fish C1qA evolved from an ancestral protein

  2. C1qA globular domain (C1qAgD) was expressed, purified and crystallized.

Human Complement Component 1, Q Subcomponent, A Chain (C1QA) interaction partners

  1. this studies show binding of VWF (show VWF Proteins) to C1q and thus a direct interaction between starter molecules of hemostasis and the classical pathway of complement

  2. Cerebrospinal fluid (CSF (show CSF2 Proteins)) soluble complement receptor 2 (sCR2 (show RBMS1 Proteins)) levels correlated significantly both with CSF (show CSF2 Proteins) complements C3 and C1q as well as to a disease severity measure.

  3. This study reveled that C1QA having a central role in the bipolar disease and schizophrenia manifestation.

  4. no significant association found to either rs15940 (C1QA) or rs172378 (C1QC (show C1QC Proteins)) when analysed in just Parkinson disease cases , just controls or combined

  5. Our findings showed that Brugia malayi Calreticulin (show CALR Proteins) (BmCRT) is responsible for the prevention of classical complement pathway activation via its interaction with the first component C1q of the human host

  6. interaction with calreticulin (show CALR Proteins) controls the phagocyte inflammatory status

  7. A newly characterized leech calreticulin (show CALR Proteins) (HmCalR) has been shown to interact with C1q and participate to the HmC1q-dependent microglia accumulation.

  8. Both CERT (show COL4A3BP Proteins) isoforms, when immobilized, were found to bind the globular head region of C1q and to initiate the classical complement pathway. C1q binds endogenous CERTL (show COL4A3BP Proteins) on the surface of apoptotic cells.

  9. Most likely, C1q bridges calreticulin (show CALR Proteins) on the parasite surface with its receptor orthologue on human placental cells, thus facilitating the first encounter between the parasite and the fetal derived placental tissue.

Mouse (Murine) Complement Component 1, Q Subcomponent, A Chain (C1QA) interaction partners

  1. findings show that C1q rather than FcgammaRs controls the Ab-mediated Ag uptake and its presentation by spleen APC (show APC Proteins) subsets to T cells

  2. Demonstrate local synthesis of complement proteins by both PDGFRbeta-positive pericytes and CD45 (show PTPRC Proteins)-positive cells in kidney fibrosis.

  3. Deleting C1qa gene significantly reduces synaptic pruning by Grn (show GRN Proteins)(-/-) microglia and mitigates neurodegeneration, behavioral phenotypes, and premature mortality in Grn (show GRN Proteins)(-/-) mice; results uncover a previously unrecognized role of progranulin (show GRN Proteins) in suppressing aberrant microglia activation during aging.

  4. developmental mechanisms of C1qa may be re-engaged during injury response

  5. C1q is involved in the pristane-mediated enhanced inflammatory response to TLR7 (show TLR7 Proteins) stimulation.

  6. C1q is involved in the pristane-mediated enhanced inflammatory response to TLR7 (show TLR7 Proteins) stimulation.

  7. Data (including data from studies in mutant mice) suggest exercise prevents age-related neurovascular decline, up-regulation of C1qa, and down-regulation of astrocytic Apoe (show APOE Proteins); this preventive effect of exercise does not occur in Apoe (show APOE Proteins)-deficient mice.

  8. critical role in activation of beta-catenin (show CTNNB1 Proteins) signalling in hypertensive arterial remodelling

  9. Data (including data on knockout mice) suggest, in absence of Trem2 (triggering receptor expressed on myeloid cells 2 (show TREM2 Proteins)), pulmonary macrophages selectively produce elevated levels of C1q resulting in enhanced phagocytosis during pneumococcal pneumonia.

  10. C1q induction and global complement pathway activation do not contribute to ALS toxicity in mutant SOD1 (show SOD1 Proteins) mice.

C1QA Protein Profile

Protein Summary

This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the A-chain polypeptide of human complement subcomponent C1q.

Alternative names and synonyms associated with C1QA

  • complement component 1, q subcomponent, A chain (C1QA)
  • complement component 1, q subcomponent, A chain (c1qa)
  • complement component 1, q subcomponent, A chain (C1qa)
  • complement component 1, q subcomponent, alpha polypeptide (C1qa)
  • AI255395 protein
  • C1q protein
  • C1QA protein
  • zgc:109903 protein

Protein level used designations for C1QA

complement component 1, q subcomponent, alpha polypeptide , complement C1q subcomponent subunit A , complement component 1, q subcomponent, A chain , complement component C1q, A chain , complement C1qA

GENE ID SPECIES
419504 Gallus gallus
553548 Danio rerio
708477 Macaca mulatta
749231 Pan troglodytes
712 Homo sapiens
298566 Rattus norvegicus
534961 Bos taurus
445461 Sus scrofa
12259 Mus musculus
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