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Browse our anti-Complement Component 5 (C5) Antibodies

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anti-Complement Component 5 Antibodies (C5)
On are 157 Complement Component 5 (C5) Antibodies from 22 different suppliers available. Additionally we are shipping Complement Component 5 Kits (52) and Complement Component 5 Proteins (19) and many more products for this protein. A total of 233 Complement Component 5 products are currently listed.
C5, C5a, C5b, CPAMD4, Hc, He, LOC565774, RGD1561905
list all antibodies Gene Name GeneID UniProt
C5 727 P01031
C5 362119  
C5 15139 P06684

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Top referenced anti-Complement Component 5 Antibodies

  1. Human Monoclonal C5 Primary Antibody for ICFC - ABIN2660803 : Tack, Morris, Prahl: Fifth component of human complement: purification from plasma and polypeptide chain structure. in Biochemistry 1979 (PubMed)
    Show all 4 references for ABIN2660803

  2. Human Monoclonal C5 Primary Antibody for BP, ELISA - ABIN257905 : Kola, Baensch, Bautsch, Klos, Köhl: Analysis of the C5a anaphylatoxin core domain using a C5a phage library selected on differentiated U937 cells. in Molecular immunology 1999 (PubMed)
    Show all 3 references for ABIN257905

  3. Human Monoclonal C5 Primary Antibody for EIA, Func - ABIN181110 : Peng, Hao, Madri, Su, Elias, Stahl, Squinto, Wang: Role of C5 in the development of airway inflammation, airway hyperresponsiveness, and ongoing airway response. in The Journal of clinical investigation 2005 (PubMed)
    Show all 2 references for ABIN181110

  4. Human Polyclonal C5 Primary Antibody for EIA, FACS - ABIN453545 : McClure, Lunt, Eyre, Ke, Thomson, Hinks, Bowes, Gibbons, Plant, Wilson, Marinou, Morgan, Emery, Steer, Hocking, Reid, Wordsworth, Harrison, Worthington, Barton: Investigating the viability of genetic screening/testing for RA susceptibility using combinations of five confirmed risk loci. in Rheumatology (Oxford, England) 2009 (PubMed)
    Show all 2 references for ABIN453545

  5. Human Monoclonal C5 Primary Antibody for ELISA (Detection), Func - ABIN1106795 : Fung, Lu, Fure, Sun, Sun, Shi, Dou, Su, Swanson, Mollnes: Pre-neutralization of C5a-mediated effects by the monoclonal antibody 137-26 reacting with the C5a moiety of native C5 without preventing C5 cleavage. in Clinical and experimental immunology 2003 (PubMed)

More Antibodies against Complement Component 5 Interaction Partners

Human Complement Component 5 (C5) interaction partners

  1. In an arterial thrombosis model, plasminogen activator administration increased C5a levels. Overall, these findings suggest plasmin bridges thrombosis and the immune response by liberating C5a and inducing MAC assembly.

  2. C5 rs2269067 GG genotype confers risk for proliferative diabetic retinopathy of type 2 diabetes in Chinese Han population (associated with an elevated C5 mRNA expression and an increased IL-6 (show IL6 Antibodies) production)

  3. C5a can induce the expression of TLR4 (show TLR4 Antibodies) in retinal pigment epithelial cells.

  4. sublingual immunotherapy for Japanese cedar pollinosis affects levels of IL-17A (show IL17A Antibodies) and complement components 3a and 5a

  5. These results identify complement activation product C5a as a priming signal for RPE (show RPE Antibodies) cells that allows for subsequent inflammasome activation by stimuli such as lipofuscin-mediated photooxidative damage.

  6. a significant up-regulation (173 fold increase, p < 0.0001) in the expression of inflammatory complement component 5 (C5) in endometriosis was detected for the first time.

  7. Data show that combined inhibition of complement 3 and 5 and CD14 antigen (show CD14 Antibodies) significantly reduced E. coli-induced cytokines.

  8. Rs2900180 in C5-TRAF1 (show TRAF1 Antibodies) and linked variants in a 66Kb region were associated with radiographic progression in ACPA (show PRTN3 Antibodies)-negative RA

  9. The C5 rs2269067 GG genotype confers risk for AAU in a Chinese population and is associated with an elevated C5 serum concentration and an increased IL-17 (show IL17A Antibodies) production.

  10. TRAF1 (show TRAF1 Antibodies)/C5 rs10818488 polymorphism is not a genetic risk factor for acquired aplastic anemia in a Chinese population.

Mouse (Murine) Complement Component 5 (C5) interaction partners

  1. Choroidal neovascularization lesions trigger a systemic immune response, augmenting local ocular inflammation via the infiltration of IL-17 (show IL17A Antibodies)-producing gamma-delta T-cells, which are presumably recruited to the eye in a C5a-dependent manner.

  2. Data (including data from studies in knockout mice) suggest that C5aR/C5aR (show C5AR1 Antibodies) (complement C5a/anaphylatoxin C5a Receptor) signaling pathway is involved in neurocognitive injury in uninfected pups induced by malaria in pregnancy.

  3. Carboxypeptidase B2 (show CPB2 Antibodies) deficiency reveals that complement C5a exacerbates infection in a murine polymicrobial sepsis model.

  4. our results suggest that the detrimental effects of C5a in this model are partly mediated through CCR5 (show CCR5 Antibodies) activation downstream of C5aR1 (show C5AR1 Antibodies), which may be evaluated for potential therapeutic exploitation in ALI/ARDS.

  5. C5a signaling increases the expression of the chemokine (show CCL1 Antibodies) monocyte chemoattractant protein-1 (show CCL2 Antibodies) in hepatic metastases of colon cancer

  6. Properdin (show CFB Antibodies) provides protection from Citrobacter rodentium-induced intestinal inflammation in a C5a/IL-6 (show IL6 Antibodies)-dependent manner.

  7. C5a produced during lung injury binds to C5aR (show C5AR1 Antibodies) in alveolar macrophages, initiates downstream signaling that promotes autophagy.

  8. Protein kinase C-delta (show PKCd Antibodies) mediates sepsis-induced activation of complement 5a and urokinase-type plasminogen activator (show PLAU Antibodies) signaling in macrophages

  9. This work reveals an essential role for C5L2 (show GPR77 Antibodies) in C5a-triggered, AP2 (show TFAP2A Antibodies)-dependent C5aR (show C5AR1 Antibodies) internalization and downstream ERK (show EPHB2 Antibodies) signaling.

  10. IFN-gamma (show IFNG Antibodies)-producing NKT (show CTSL1 Antibodies) cells enhance C5a generation via IL-10 (show IL10 Antibodies)-mediated inhibition of CD55 (show CD55 Antibodies) expression on neutrophils, thereby exacerbating sepsis.

Complement Component 5 (C5) Antigen Profile

Antigen Summary

The protein encoded by this gene is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge. An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase. The C5b macromolecular cleavage product can form a complex with the C6 complement component, and this complex is the basis for formation of the membrane attack complex, which includes additional complement components. Mutations in this gene cause complement component 5 deficiency, a disease where patients show a propensity for severe recurrent infections. Defects in this gene have also been linked to a susceptibility to liver fibrosis and to rheumatoid arthritis.

Alternative names and synonyms associated with Complement Component 5 (C5)

  • complement component 5 (C5) antibody
  • similar to complement component C5-1 (LOC565774) antibody
  • hemolytic complement (Hc) antibody
  • C5 antibody
  • C5a antibody
  • C5b antibody
  • CPAMD4 antibody
  • Hc antibody
  • He antibody
  • LOC565774 antibody
  • RGD1561905 antibody

Protein level used designations for C5

complement component 5 , similar to complement component C5-1 , C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4 , C5a anaphylatoxin , anaphylatoxin C5a analog , complement C5 , prepro-C5 , anaphylatoxin , complement component C5 , complement C5a anaphylatoxin

464703 Pan troglodytes
565774 Danio rerio
700467 Macaca mulatta
100606437 Nomascus leucogenys
727 Homo sapiens
362119 Rattus norvegicus
100733000 Cavia porcellus
414437 Sus scrofa
512045 Bos taurus
474816 Canis lupus familiaris
417122 Gallus gallus
101121825 Ovis aries
15139 Mus musculus
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