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anti-Human Complement Factor H antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended Complement Factor H Antibody (supplied by: Log in to see )

Antigen
Complement Factor H (CFH) Antibodies
  • AHUS1
  • AMBP1
  • ARMD4
  • ARMS1
  • CFH
  • CFHL3
  • fH
  • Fh
  • FH
  • FHL1
  • HF
  • HF1
  • HF2
  • HUS
  • im:7147412
  • Mud-1
  • NOM
  • Sas-1
  • Sas1
  • si:ch211-207o17.2
Epitope
AA 751-780, Middle Region
25
17
17
13
10
5
3
2
2
2
2
1
1
1
1
Reactivity
Human
204
30
24
3
3
2
2
1
1
Host
Rabbit
92
71
31
27
2
1
Clonality
Polyclonal
Conjugate
This Complement Factor H antibody is un-conjugated
17
11
5
3
3
3
2
2
2
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
138
124
43
38
31
22
21
17
13
11
8
6
5
4
2
1
1
1
1
1
1
Supplier
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Catalog No. ABIN951646
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.34458184 ABIN337307 IHC (p) ELISA WB Goat Internal Region Log in to see Polyclonal
0.34458184 ABIN462334 IHC (p) IP ELISA WB Mouse IgG1 Log in to see OX-24
0.34458184 ABIN615210 EIA IHC (p) Sheep Log in to see Polyclonal
0.34458184 ABIN364283 FACS IHC (p) IP ELISA WB Mouse IgG1 Log in to see OX-24
0.34458184 ABIN410774 IHC (p) ELISA Sheep Log in to see Polyclonal
0.00089488085 ABIN654896 IF IHC (p) WB Rabbit Ig AA 751-780, Center Log in to see Polyclonal 2
0.00089488085 ABIN492503 EIA FACS IHC (p) IP WB Mouse IgG1 Log in to see OX-24
0.00089488085 ABIN372860 EIA IHC (p) WB Goat IgG Internal Region Log in to see Polyclonal
0.00089488085 ABIN2854706 IHC (p) WB Rabbit IgG Internal Region Log in to see Polyclonal
0.00089488085 ABIN1101458 IHC (p) ELISA Goat IgG Log in to see Polyclonal
0.00089488085 ABIN957771 IHC (p) IP ELISA Mouse IgG2b, kappa Log in to see 63G5
0.00089488085 ABIN492561 EIA IHC (p) IP WB Mouse IgG1 Log in to see OX-24
0.00089488085 ABIN1832834 IHC (p) WB Rabbit IgG AA 527-618 Log in to see Polyclonal
0.00089488085 ABIN733840 IHC (p) WB Biotin Rabbit IgG AA 1160-1210 Log in to see Polyclonal
0.00089488085 ABIN733847 IHC (p) WB HRP Rabbit IgG AA 1160-1210 Log in to see Polyclonal
0.00089488085 ABIN1724459 IHC (p) IP ELISA Mouse IgG2b kappa Log in to see 63G5
0.00089488085 ABIN1723178 FACS IHC (p) IP ELISA WB Mouse IgG1 Log in to see OX-24
0.00089488085 ABIN1858384 ICC IHC (fro) IHC (p) ELISA WB Mouse IgG AA 860-1231 Log in to see
0.00089488085 ABIN733838 IF (p) IHC (p) WB Rabbit IgG AA 1160-1210 Log in to see Polyclonal
0.00089488085 ABIN1421104 IHC (p) WB HRP Rabbit IgG Log in to see Polyclonal

Similar anti-Complement Factor H Antibodies

Application / Reactivity Human
ELISA 118 Antibodies
Enzyme Immunoassay (EIA) 9 Antibodies
Flow Cytometry (FACS) 20 Antibodies
Immunoassay (IA) 2 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 3 Antibodies
Immunodiffusion (ID) 14 Antibodies
Immunoelectrophoresis (IEP) 2 Antibodies
Immunofluorescence (IF) 18 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 22 Antibodies
Immunohistochemistry (IHC) 45 Antibodies
Immunohistochemistry (Acetone-fixed) (IHC (af)) 1 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 1 Antibodies
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 1 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 9 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 37 Antibodies
Immunoprecipitation (IP) 31 Antibodies

General

Antigen Complement Factor H (CFH) Antibodies
Epitope AA 751-780, Middle Region
(25), (17), (17), (13), (10), (5), (3), (2), (2), (2), (2), (1), (1), (1), (1)
Reactivity Human
(204), (30), (24), (3), (3), (2), (2), (1), (1)
Host Rabbit
(92), (71), (31), (27), (2), (1)
Clonality
Polyclonal
Conjugate This Complement Factor H antibody is un-conjugated
(17), (11), (5), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(138), (124), (43), (38), (31), (22), (21), (17), (13), (11), (8), (6), (5), (4), (2), (1), (1), (1), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-Complement Factor H Antibody

Target Details Complement Factor H Application Details Handling References for anti-Complement Factor H Antibody (ABIN951646) Images
Specificity This antibody reacts to CFH.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Immunogen KLH conjugated synthetic peptide between 751-780 amino acids from the Central region of human CFH
Isotype Ig

Target Details Complement Factor H

Product Details anti-Complement Factor H Antibody Application Details Handling References for anti-Complement Factor H Antibody (ABIN951646) Images back to top
Antigen
Background This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short concensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.Synonyms: CFH, H factor 1, HF, HF1, HF2
Molecular Weight 139096 Da
Gene ID 3075
NCBI Accession NP_000177
Research Area Coagulation, Complement Factors
Pathways Complement System

Application Details

Product Details anti-Complement Factor H Antibody Target Details Complement Factor H Handling References for anti-Complement Factor H Antibody (ABIN951646) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-Complement Factor H Antibody Target Details Complement Factor H Application Details References for anti-Complement Factor H Antibody (ABIN951646) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-Complement Factor H Antibody (ABIN951646)

Product Details anti-Complement Factor H Antibody Target Details Complement Factor H Application Details Handling Images back to top
Background publications

Dieterich, Hammerschmidt, Richter, Skerka, Wallich, Matuschka, Zipfel, Kraiczy: "Inadequate binding of immune regulator factor H is associated with sensitivity of Borrelia lusitaniae to human complement." in: Infection and immunity, Vol. 78, Issue 11, pp. 4467-76, 2010

Sofat, Casas, Kumari, Talmud, Ireland, Kivimaki, Marmot, Hughes, Thom, Ebrahim, Whittaker, Smeeth, Lawlor, Humphries, Hingorani: "Genetic variation in complement factor H and risk of coronary heart disease: eight new studies and a meta-analysis of around 48,000 individuals." in: Atherosclerosis, Vol. 213, Issue 1, pp. 184-90, 2010

Davila, Wright, Khor, Sim, Binder, Breunis, Inwald, Nadel, Betts, Carrol, de Groot, Hermans, Hazelzet, Emonts, Lim, Kuijpers, Martinon-Torres, Salas, Zenz, Levin, Hibberd: "Genome-wide association study identifies variants in the CFH region associated with host susceptibility to meningococcal disease." in: Nature genetics, Vol. 42, Issue 9, pp. 772-6, 2010

Images

Product Details anti-Complement Factor H Antibody Target Details Complement Factor H Application Details Handling References for anti-Complement Factor H Antibody (ABIN951646) back to top
Supplier Images
Immunofluorescence (IF) image for anti-Complement Factor H antibody (CFH) (AA 751-780) (ABIN951646) Confocal immunofluorescent analysis of CFH Antibody (Center) with A549 cell followed ...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Complement Factor H antibody (CFH) (AA 751-780) (ABIN951646) CFH antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin em...
Western Blotting (WB) image for anti-Complement Factor H antibody (CFH) (AA 751-780) (ABIN951646) CFH Antibody (Center) western blot analysis in K562 cell line lysates (35µg/lane).Thi...