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Browse our anti-MASP1 (MASP1) Antibodies

Full name:
anti-Mannan-Binding Lectin serine Peptidase 1 (C4/C2 Activating Component of Ra-Reactive Factor) Antibodies (MASP1)
On www.antibodies-online.com are 55 Mannan-Binding Lectin serine Peptidase 1 (C4/C2 Activating Component of Ra-Reactive Factor) (MASP1) Antibodies from 12 different suppliers available. Additionally we are shipping MASP1 Kits (16) and MASP1 Proteins (14) and many more products for this protein. A total of 91 MASP1 products are currently listed.
Synonyms:
3MC1, AW048060, CCPII, CRARF, CRARF1, MAP1, MAp44, MASP, Masp1/3, MASP3, PRSS5, RaRF
list all antibodies Gene Name GeneID UniProt
MASP1 17174 P98064
MASP1 5648 P48740
MASP1    

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More Antibodies against MASP1 Interaction Partners

Mouse (Murine) Mannan-Binding Lectin serine Peptidase 1 (C4/C2 Activating Component of Ra-Reactive Factor) (MASP1) interaction partners

  1. study provides conclusive evidence that an intact complement LP is essential to initiate CAIA, and that MAp44 may be an appropriate treatment for inflammatory arthritis.

  2. Data indicate that co-deficiency of factor H (FH (show CFH Antibodies)) and MASP-1/MASP-3 did not ameliorate either the plasma Complement C3 (show C3 Antibodies) (C3) activation or glomerular C3 accumulation in FH-deficient mice.

  3. Within the mannose-binding lectin (show MBL2 Antibodies)/MASP complex, MASP-1 is the necessary complement component for thrombin (show F2 Antibodies)-like activity in vitro.

  4. We conclude that MASP-1 does not require binding to mannose binding lectins or ficolins to activate the alternative pathway of complement

  5. we investigated the mechanism of MASP-3 activation and its substrate using the recombinant mouse MASP-3 (rMASP-3) and several different types of MASP-deficient mice

  6. Our studies demonstrate for the first time, to our knowledge, the absolute requirement for the activity of MASP-1 protein in autoimmune-associated inflammatory tissue injury

  7. MASP-1 converted pro-Df to the active form in vitro, although the activation mechanism of pro-Df by MASP-1 is still unclear. Thus, it is clear that MASP-1 is an essential protease of both the lectin and alternative complement pathways.

  8. MASP-1 contributes to the activation of the lectin pathway, probably through the activation of MASP-2 (show MASP2 Antibodies).

Human Mannan-Binding Lectin serine Peptidase 1 (C4/C2 Activating Component of Ra-Reactive Factor) (MASP1) interaction partners

  1. described for the first time a detailed model of prothrombin (show F2 Antibodies) activation by MASP-1

  2. Fusion of MAP-1 with FH domains represents a novel therapeutic approach for selective targeting upstream and central complement activation at sites of inflammation

  3. The levels of MASP-1 and MASP-1/C1-INH (show SERPING1 Antibodies) complexes are reduced in HAE patients compared with controls. Both MASP-1 and MASP-1/C1-INH (show SERPING1 Antibodies) complexes are related to the degree of complement C4 (show C4A Antibodies) consumption

  4. Polymorphisms in MASP1 and MASP2 (show MASP2 Antibodies) genes are associated with the susceptibility or protection to infectious diseases. (Review)

  5. Because MASP-1 and MASP-2 (show MASP2 Antibodies) have been shown to interact directly with blood coagulation, elevated levels of these proteins may play a role in the enhanced thrombotic environment and consequent vascular complications in diabetes.

  6. MASP-1 cleaves prothrombin (show F2 Antibodies) and identified its cleavage sites, suggesting that MASP-1 gives rise to an alternative active form of thrombin (show F2 Antibodies) by cleaving at the cleavage site R393.

  7. MASP-1 may activate neutrophils indirectly via endothelial cells.

  8. Data indicate that MASP-1 and MASP-2 (show MASP2 Antibodies) can readily form heterodimers after dissociation and re-association, however, in the presence of Ca(2 (show CA2 Antibodies)+) exchange of subunits is slow between the homodimers.

  9. Data show that among the components of the mannose-binding lectin (MBL (show MBL2 Antibodies)) and associated serine proteases (MASPs) only MASP-1 is able to trigger response in endothelial cells (HUVECs) and the proteolytic activity of MASP-1 is essential.

  10. Polymorphisms in the MASP1 gene are associated with serum levels of MASP-1, MASP-3, and MAp44

MASP1 Antigen Profile

Antigen Summary

This gene encodes a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. The encoded protein is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway. Alternate splicing results in multiple transcript variants.

Alternative names and synonyms associated with MASP1

  • mannan-binding lectin serine peptidase 1 (Masp1) antibody
  • mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) (MASP1) antibody
  • 3MC1 antibody
  • AW048060 antibody
  • CCPII antibody
  • CRARF antibody
  • CRARF1 antibody
  • MAP1 antibody
  • MAp44 antibody
  • MASP antibody
  • Masp1/3 antibody
  • MASP3 antibody
  • PRSS5 antibody
  • RaRF antibody

Protein level used designations for MASP1

MASP-1 , complement factor MASP-3 , complement-activating component of Ra-reactive factor , mannan-binding lectin serine protease 1 , mannose-binding lectin-associated serine protease 1 , mannose-binding protein-associated serine protease , ra-reactive factor serine protease p100 , raRF , serine protease 5 , Ra-reactive factor serine protease p100

GENE ID SPECIES
17174 Mus musculus
5648 Homo sapiens
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