Browse our YES1 Proteins (YES1)

Full name:
V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1 Proteins (YES1)
On are 10 V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1 (YES1) Proteins from 8 different suppliers available. Additionally we are shipping YES1 Antibodies (154) and YES1 Kits (1) and many more products for this protein. A total of 173 YES1 products are currently listed.
c-Yes, HsT441, p60c-yes, p61-Yes, YES, YES1
list all proteins Gene Name GeneID UniProt
YES1 7525 P07947
YES1 22612 Q04736
YES1 24884  

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YES1 Proteins (YES1) by Origin

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Top referenced YES1 Proteins

  1. Human YES1 Protein expressed in Baculovirus infected Insect Cells - ABIN2004789 : Summy, Sudol, Eck, Monteiro, Gatesman, Flynn: Specificity in signaling by c-Yes. in Frontiers in bioscience : a journal and virtual library 2002 (PubMed)

More Proteins for YES1 Interaction Partners

Human V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1 (YES1) interaction partners

  1. Our results suggest that H19 (show NCKAP1 Proteins) functions as a competitive endogenous RNA (ceRNA) by acting as a sink for miR-17-5p, revealing a potential ceRNA regulatory network involving H19 (show NCKAP1 Proteins) and miR-17-5p with a role in the modulation of YES1 expression

  2. c-Yes plays an important role in migration and invasion of epithelial ovarian cancer.

  3. Up-regulation of miR (show MLXIP Proteins)-210 inhibits hepatocellular carcinoma cell proliferation. Yes1 is a target of miR (show MLXIP Proteins)-210 and affects cell proliferation in HCC (show FAM126A Proteins).

  4. findings indicate that miR (show MLXIP Proteins)-203 induces the apoptosis of KB cells by directly targeting Yes-1, suggesting its application in anti-cancer therapeutics

  5. Results demonstrate a unique role for Yes in phosphorylation of FAK (show PTK2 Proteins) and in promoting PCa (show FLVCR1 Proteins) metastasis. Therefore, phosphorylated FAK (show PTK2 Proteins) Y861 and increased Yes expression may be predictive markers for PCa (show FLVCR1 Proteins) metastasis.

  6. results indicated that miR-17-5p might play a role in human ovarian cancer by up-regulating YES1 expression.

  7. Increased YES/SFK activation might serve as a clinical biomarker for predicting tumor resistance to IGF-1R (show IGF1R Proteins) inhibition.

  8. YES1 and YAP (show YAP1 Proteins) transcript levels were higher in liver metastases of patients with colon cancer after 5FU-based neoadjuvant chemotherapy.

  9. YES kinase as a proximal glucose-specific signal in the Cdc42 (show CDC42 Proteins)-signaling cascade.

  10. we identified CRKL (show CRKL Proteins)/YES as critical interrelated pathways necessary for rhabdomyosarcoma cell growth and survival and suggest a potential therapeutic role of SRC (show SRC Proteins) family kinase inhibition in the treatment of rhabdomyosarcoma.

Zebrafish V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1 (YES1) interaction partners

  1. investigated signaling pathways in early development by comparison of the phosphoproteome of wild type embryos with Fyn (show FYN Proteins)/Yes knockdown embryos that display specific convergence and extension cell movement defects

Mouse (Murine) V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1 (YES1) interaction partners

  1. Ganglioside GD3 enhances invasiveness of gliomas by forming a complex with PDGFRalpha and Yes Kinase.

  2. serum also activates TEAD-dependent transcription in a time- and dose-dependent manner and we identify Inter-alpha-inhibitor (IalphaI) as a component in serum capable of activating the Yes/YAP (show YAP1 Proteins)/TEAD pathway

  3. Differentiation of embryonic stem cells is driven by c-Src (show SRC Proteins) is antagonized by c-Yes.

  4. The antiapoptotic effect of YES1 activation in response to testicular heat insult may mediate via the regulation of extracellular signal-regulated kinase (ERK (show EPHB2 Proteins))/metastasis-associated 1 (MTA1 (show MTA1 Proteins)) cascade.

  5. Results suggest that LKB1 (show STK11 Proteins) inactivation in the context of RAS activation facilitates metastasis by inducing an SFK-dependent expansion of a prometastatic, CD24 (show CD24 Proteins)(+) tumor subpopulation.

  6. YAP (show YAP1 Proteins), TEAD2 (show TEAD2 Proteins) and Yes are highly expressed in self-renewing embryonic stem cells, and are activated by LIF (show LIF Proteins).

  7. eIF4E (show EIF4E Proteins) and yes have cooperative roles in oncogenic transformation

  8. Data show that in response to angiotensin II, the ability of ERK1/2 to remain within the cytoplasm or translocate into the nucleus is controlled by c-Src (show SRC Proteins)/Yes/Fyn (show FYN Proteins) or heterotrimeric G protein/PKCzeta (show PRKCZ Proteins) signaling, respectively.

  9. Data imply that distinct modes of spatial activation and membrane delivery, under the control of specific acylation attachment sequences and endosome sub-type requirements, define distinct properties of the three SFKs (Src (show SRC Proteins) family kinases).

  10. Binding of CD95 Ligand to CD95 on glioblastoma cells recruit Yes and the p85 subunit of phosphatidylinositol 3-kinase to CD95, which signal invasion via the glycogen synthase kinase 3-beta pathway and subsequent expression of matrix metalloproteinases.

YES1 Protein Profile

Protein Summary

This gene is the cellular homolog of the Yamaguchi sarcoma virus oncogene. The encoded protein has tyrosine kinase activity and belongs to the src family of proteins. This gene lies in close proximity to thymidylate synthase gene on chromosome 18, and a corresponding pseudogene has been found on chromosome 22.

Alternative names and synonyms associated with YES1

  • v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 (YES1)
  • v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 (yes1)
  • v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 (Yes1)
  • Yamaguchi sarcoma viral (v-yes) oncogene homolog 1 (Yes1)
  • c-Yes protein
  • HsT441 protein
  • p60c-yes protein
  • p61-Yes protein
  • YES protein
  • YES1 protein

Protein level used designations for YES1

viral oncogene yes-1 homolog 1 , v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 , tyrosine-protein kinase Yes , viral oncogene yes-1 homolog 1-like , proto-oncogene tyrosine-protein kinase Yes-like , Yamaguchi sarcoma oncogene , cellular yes-1 protein , proto-oncogene c-Yes , proto-oncogene tyrosine-protein kinase YES , protein-tyrosine kinase , tyrosine-protein kinase yes , yes-kinase , c-yes proto-oncogene , p61-Yes , proto-oncogene tyrosine-protein kinase Yes , viral oncogene yes homolog , Yamagichi sarcoma viral (v-yes-1) oncogene homolog 1 , Yamaguchi sarcoma viral oncogene homolog 1

455322 Pan troglodytes
490532 Canis lupus familiaris
493548 Xenopus (Silurana) tropicalis
697099 Macaca mulatta
100346628 Oryctolagus cuniculus
100392850 Callithrix jacchus
100472271 Ailuropoda melanoleuca
7525 Homo sapiens
407620 Danio rerio
403917 Canis lupus familiaris
396238 Gallus gallus
507632 Bos taurus
100721080 Cavia porcellus
379629 Xenopus laevis
22612 Mus musculus
24884 Rattus norvegicus
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