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Browse our anti-PIK3C2A (PIK3C2A) Antibodies

Full name:
anti-Phosphoinositide-3-Kinase, Class 2, alpha Polypeptide Antibodies (PIK3C2A)
On www.antibodies-online.com are 116 Phosphoinositide-3-Kinase, Class 2, alpha Polypeptide (PIK3C2A) Antibodies from 14 different suppliers available. Additionally we are shipping PIK3C2A Kits (9) and PIK3C2A Proteins (4) and many more products for this protein. A total of 135 PIK3C2A products are currently listed.
Synonyms:
CPK, Cpk-m, DKFZp469H1410, PI3-K-C2(ALPHA), PI3-K-C2A, PI3KC2, PIK3C2A
list all antibodies Gene Name GeneID UniProt
PIK3C2A 361632  
PIK3C2A 18704 Q61194
PIK3C2A 5286 O00443

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Most Popular Reactivities for anti-PIK3C2A (PIK3C2A) Antibodies

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anti-Rat (Rattus) PIK3C2A Antibodies:

anti-Mouse (Murine) PIK3C2A Antibodies:

anti-Human PIK3C2A Antibodies:

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Top referenced anti-PIK3C2A Antibodies

  1. Dog (Canine) Polyclonal PIK3C2A Primary Antibody for IHC (p) - ABIN374410 : Molz, Chen, Hirano, Williams: Cpk is a novel class of Drosophila PtdIns 3-kinase containing a C2 domain. in The Journal of biological chemistry 1996 (PubMed)

  2. Mouse (Murine) Polyclonal PIK3C2A Primary Antibody for IHC (p), WB - ABIN655800 : Mathew, Skuli, Mucaj, Lee, Zinn, Sathyan, Imtiyaz, Zhang, Davuluri, Rao, Venneti, Lal, Lathia, Rich, Keith, Minn, Simon: miR-218 opposes a critical RTK-HIF pathway in mesenchymal glioblastoma. in Proceedings of the National Academy of Sciences of the United States of America 2014 (PubMed)

More Antibodies against PIK3C2A Interaction Partners

Xenopus laevis Phosphoinositide-3-Kinase, Class 2, alpha Polypeptide (PIK3C2A) interaction partners

  1. This is how other pik3c2a SCR map but I think more specific mapping may be appropriate (Class II Phosphatidylinositol 3-Kinases).

Mouse (Murine) Phosphoinositide-3-Kinase, Class 2, alpha Polypeptide (PIK3C2A) interaction partners

  1. PI3KC2a knockdown results in rerouting of insulin (show INS Antibodies) signaling and pancreatic beta cell proliferation.

  2. Heterozygous PI3K-C2-alpha inactivation in platelets led to reduction in phosphatidylinositol 3-monophosphate and a mislocalization of several membrane skeleton proteins known to control the interactions between the plasma membrane and cytoskeleton.

  3. Data (including data from knockout mice) suggest that Pi3kc2a participates in tumor angiogenesis. [REVIEW]

  4. Our studies indicate that while Vps34 (show PIK3C3 Antibodies) is the main PI3P source during autophagy, class II PI3Ks also significantly contribute to PI3P generation and regulate AP biogenesis.

  5. PI3K-C2alpha has a crucial role in vascular formation and barrier integrity

  6. PI3KC2alpha-deficient mice developed chronic renal failure and exhibited a range of kidney lesions, including glomerular crescent (show SFRP5 Antibodies) formation and renal tubule defects in early disease, which progressed to diffuse mesangial sclerosis.

  7. phosphoinositide 3-kinase C2alpha has a role in insulin (show INS Antibodies) signaling

Human Phosphoinositide-3-Kinase, Class 2, alpha Polypeptide (PIK3C2A) interaction partners

  1. PI3KC2a knockdown results in rerouting of insulin (show INS Antibodies) signaling and pancreatic beta cell proliferation.

  2. MiR (show MLXIP Antibodies)-206 regulates endothelial progenitor cell activities by targeting PIK3C2alpha expression.The role of PIK3C2alpha in endothelial progenitor cell function in coronary artery disease

  3. PI3KC2alpha has a role in regulating shear-dependent platelet adhesion via regulation of membrane structure, rather than acute signalling

  4. a model of S. flexneri dissemination is proposed in which the formation of vacuole-like protrusions is mediated by the PIK3C2A-dependent production of the signaling lipid phosphatidylinositol 3-phosphate in the protrusion membrane

  5. Data (including data from knockout mice) suggest that PI3KC2a participates in tumor angiogenesis. [REVIEW]

  6. These observations indicate that PI3K-C2alpha plays the pivotal role in TGFbeta (show TGFB1 Antibodies) receptor endocytosis and thereby Smad2 (show SMAD2 Antibodies)/3 signaling, participating in angiogenic actions of TGFbeta (show TGFB1 Antibodies).

  7. Class II enzyme PI3K-C2beta (show PIK3C2B Antibodies) and the class IB isozyme p110gamma (show PIK3CG Antibodies) mainly regulate the S1P (show MBTPS1 Antibodies)- and high density lipoprotein (HDL (show HSD11B1 Antibodies))-dependent endothelial cell (EC) migration and PI3K-C2alpha primarily controls EC survival

  8. PI3K-C2alpha plays the crucial role in S1P(1) internalization into the intracellular vesicular compartment, Rac1 activation on endosomes, and thereby migration through regulating vesicular trafficking in ECs

  9. These data suggest a general role for PI3KC2alpha in regulating physiologically relevant dynamin (show DNM1 Antibodies)-independent internalization pathways.

  10. Phosphoinositide 3-kinase C2alpha was found to be differentially regulated by alpha(v)beta(3) and alpha(v)beta(5) integrin, and may represent a new regulatory pathway of cell migration downstream of integrin engagement.

PIK3C2A Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling.

Alternative names and synonyms associated with PIK3C2A

  • phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha (Pik3c2a) antibody
  • phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha (PIK3C2A) antibody
  • phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha (pik3c2a) antibody
  • phosphoinositide-3-kinase, class 2, alpha polypeptide (pik3c2a) antibody
  • phosphoinositide-3-kinase, class 2, alpha polypeptide (PIK3C2A) antibody
  • phosphatidylinositol 3-kinase, C2 domain containing, alpha polypeptide (Pik3c2a) antibody
  • CPK antibody
  • Cpk-m antibody
  • DKFZp469H1410 antibody
  • PI3-K-C2(ALPHA) antibody
  • PI3-K-C2A antibody
  • PI3KC2 antibody
  • PIK3C2A antibody

Protein level used designations for PIK3C2A

phosphatidylinositol 3-kinase, C2 domain containing, alpha polypeptide , phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit alpha , phosphoinositide-3-kinase, class 2, alpha polypeptide , phosphoinositide-3-kinase, class 2 alpha polypeptide , pi3-k-c2(alpha) , Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide , PI3K-C2-alpha , p170 , phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha , phosphoinositide 3-kinase-C2-alpha , ptdIns-3-kinase C2 subunit alpha , C2-containing phosphatidylinositol kinase , PI3K-C2alpha

GENE ID SPECIES
361632 Rattus norvegicus
451052 Pan troglodytes
537790 Bos taurus
100038240 Xenopus (Silurana) tropicalis
100056431 Equus caballus
100380949 Xenopus laevis
100481616 Ailuropoda melanoleuca
100172544 Pongo abelii
100548137 Meleagris gallopavo
100557407 Anolis carolinensis
100597578 Nomascus leucogenys
18704 Mus musculus
5286 Homo sapiens
485399 Canis lupus familiaris
100623497 Sus scrofa
100340704 Oryctolagus cuniculus
100457125 Pongo abelii
423070 Gallus gallus
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