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PTK2B Protein tyrosine Kinase 2 beta ELISA Kits (PTK2B)
On www.antibodies-online.com are 21 PTK2B Protein tyrosine Kinase 2 beta (PTK2B) ELISA Kits from 7 different suppliers available. Additionally we are shipping PTK2B Antibodies (257) and PTK2B Proteins (14) and many more products for this protein. A total of 310 PTK2B products are currently listed.
Synonyms:
Akt, CADTK, CAKB, CAKbeta, E430023O05Rik, FADK2, FAK2, PKB, PKB/Akt, PKBalpha, PTK, Pyk2, Rac, Raftk
list all ELISA KIts Gene Name GeneID UniProt
PTK2B 24185 P47196
PTK2B 11651 P31750
PTK2B 2185 Q14289

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More ELISA Kits for PTK2B Interaction Partners

Mouse (Murine) PTK2B Protein tyrosine Kinase 2 beta (PTK2B) interaction partners

  1. TSC1 (show TSC1 ELISA Kits)/TSC2 (show TSC2 ELISA Kits) complex upregulation of OPN (show SPP1 ELISA Kits) expression is mediated by transcription factor SOX9 (show SOX9 ELISA Kits) in an mTOR (show FRAP1 ELISA Kits)-independent manner. Moreover, ablation of OPN (show SPP1 ELISA Kits) by deficient TSC1 (show TSC1 ELISA Kits)/TSC2 (show TSC2 ELISA Kits) complex contributed to inactivation of AKT (show AKT1 ELISA Kits) in TSC (show SLC12A3 ELISA Kits) cells

  2. Our results suggest that increasing Akt (show AKT1 ELISA Kits)/ NF-kappaB (show NFKB1 ELISA Kits) is a crucial mediator of skin aging, which can increase the susceptibility of cell transformation.

  3. findings highlight a pivotal link between an epigenetic regulator, WHSC1, and key intracellular signaling molecules, AKT, RICTOR, and Rac1, to drive prostate cancer metastasis.

  4. Studies indicate that the Pten+/- genotype displayed neoplasia in multiple organs, including the endometrium and that the Pten is a key regulatory player in the PI3K/PTEN/AKT (show AKT1 ELISA Kits) pathway.

  5. a simple, linear, four-compartment ordinary differential equation (ODE) model of Akt (show AKT1 ELISA Kits) activation that tracks both the biochemical state and the physical location of Akt (show AKT1 ELISA Kits), is reported.

  6. Psgl-1 (show SELPLG ELISA Kits) deficiency accelerates bleomycin-induced lung fibrosis and inflammation in mice through activating the PI3K/AKT (show AKT1 ELISA Kits) axis.

  7. Data show that docetaxel, rapamycin and tanespimycin multi-drug loaded micelles targeted against HSP90 (show HSP90 ELISA Kits) and the PI3K/AKT (show AKT1 ELISA Kits)/mTOR (show FRAP1 ELISA Kits) pathway in prostate cancer.

  8. results show that Pyk2 contributes to cytotoxic T lymphocyte(CTL) migration by regulating detachment of CTL at the trailing edge, which could explain why Pyk2 is important for chemotactic and migratory responses.

  9. Furthermore, Leishmania RNA virus 1-induced TLR-3 (show TLR3 ELISA Kits) activation promoted parasite persistence by enhancing macrophage survival through Akt (show AKT1 ELISA Kits) activation in a manner partially dependent on miR (show MLXIP ELISA Kits)-155.

  10. Collectively, these findings showed that SA suppressed mammary gland development of pubertal mice, which was coincident with the SA-inhibited HC11 (show CCL2 ELISA Kits) proliferation, and was associated with inhibition of PI3K/Akt (show AKT1 ELISA Kits) signaling pathway through activation of GPR120 (show O3FAR1 ELISA Kits).

Human PTK2B Protein tyrosine Kinase 2 beta (PTK2B) interaction partners

  1. Our findings suggest that Pyk2 plays an important role in the coordination of stabilization of beta-catenin (show CTNNB1 ELISA Kits) in the crosstalk between Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) and Wnt (show WNT2 ELISA Kits)/Ca(2 (show CA2 ELISA Kits)+) signaling pathways upon Wnt3a (show WNT3A ELISA Kits) stimulation in differentiating hNPCs.

  2. STIM1 (show STIM1 ELISA Kits)-induced Ca(2 (show CA2 ELISA Kits)+) signaling activates Pyk2 to inhibit the interaction of VE-PTP (show PTPRB ELISA Kits) and VE-cadherin (show CDH5 ELISA Kits) and hence increase endothelial permeability.

  3. Ascites and CCL18 (show CCL18 ELISA Kits) stimulate the phosphorylation and expression of Pyk2, which positively regulates ascites-induced ovarian cancer cell migration.

  4. We demonstrated trophoblast cytoprotection by intervention with supraphysiological concentrations of relaxin (show 0 ELISA Kits), a process in part mediated through the PI3-kinase (show PIK3CA ELISA Kits)-Akt/PKB (show AKT1 ELISA Kits) cell survival pathway. These results provide further rationale for clinical investigation of relaxin (show 0 ELISA Kits) as a potential therapeutic in preeclampsia.

  5. PTK2B polymorphism (rs28834970) could modify the risk of late-onset Alzheimer's disease (LOAD), and PTK2B polymorphism (rs28834970) and APOE may interact to increase LOAD risk in a Han Chinese population.

  6. Studies suggest that PYK2 is a common downstream effector of ErbB (show EGFR ELISA Kits) and IL8 (show IL8 ELISA Kits) receptors, and that PYK2 integrates their signaling pathways through a positive feedback loop to potentiate breast cancer invasion.

  7. Pyk2 is a key downstream signaling molecules of CCR7 (show CCR7 ELISA Kits) in SCCHN, which promotes SCCHN tumorigenesis and progression.

  8. Phosphoproteomic analysis identifies FAK2 as a potential therapeutic target for tamoxifen resistance in breast cancer.

  9. Pyk2-focal adhesion targeting domain interacts with and binds to leupaxin (show LPXN ELISA Kits).

  10. Src (show SRC ELISA Kits) has a role in priming Pyk2 (but not FAK (show PTK2 ELISA Kits)) phosphorylation and subsequent activation downstream of integrins

Cow (Bovine) PTK2B Protein tyrosine Kinase 2 beta (PTK2B) interaction partners

  1. Ptk2b activation may play a key role in the signaling responses in ECs under hemodynamic influence [proline-rich tyrosine kinase 2]

PTK2B Antigen Profile

Antigen Summary

This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Four transcript variants encoding two different isoforms have been found for this gene.

Alternative names and synonyms associated with PTK2B

  • v-akt murine thymoma viral oncogene homolog 1 (Akt1) Elisa Kit
  • thymoma viral proto-oncogene 1 (Akt1) Elisa Kit
  • protein tyrosine kinase 2 beta (PTK2B) Elisa Kit
  • protein tyrosine kinase 2 beta (Ptk2b) Elisa Kit
  • PTK2 protein tyrosine kinase 2 beta (Ptk2b) Elisa Kit
  • PTK2B protein tyrosine kinase 2 beta (PTK2B) Elisa Kit
  • Akt Elisa Kit
  • CADTK Elisa Kit
  • CAKB Elisa Kit
  • CAKbeta Elisa Kit
  • E430023O05Rik Elisa Kit
  • FADK2 Elisa Kit
  • FAK2 Elisa Kit
  • PKB Elisa Kit
  • PKB/Akt Elisa Kit
  • PKBalpha Elisa Kit
  • PTK Elisa Kit
  • Pyk2 Elisa Kit
  • Rac Elisa Kit
  • Raftk Elisa Kit

Protein level used designations for PTK2B

AKT1 kinase , PKB alpha , RAC protein kinase alpha RAC-PK alpha , RAC-PK-alpha , RAC-alpha serine/threonine-protein kinase , murine thymoma viral (v-akt) oncogene homolog 1 , protein kinase B alpha , thymoma viral proto-oncogene 1 , protein kinase B-alpha , proto-oncogene c-AKT , related to A and C kinases , CAK-beta , FADK 2 , PTK2B protein tyrosine kinase 2 beta , calcium-dependent tyrosine kinase , calcium-regulated non-receptor proline-rich tyrosine kinase , cell adhesion kinase beta , focal adhesion kinase 2 , proline-rich tyrosine kinase 2 , protein kinase B , protein-tyrosine kinase 2-beta , related adhesion focal tyrosine kinase , CADTK , CAK beta , PTK2 protein tyrosine kinase 2 beta , cellular adhesion kinase beta , protein tyrosine kinase 2 beta

GENE ID SPECIES
24185 Rattus norvegicus
11651 Mus musculus
2185 Homo sapiens
50646 Rattus norvegicus
19229 Mus musculus
486102 Canis lupus familiaris
541008 Bos taurus
421998 Gallus gallus
100157507 Sus scrofa
100342358 Oryctolagus cuniculus
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