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ARPC3 antibody (AA 2-175)

ARPC3 Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7143089
  • Target See all ARPC3 Antibodies
    ARPC3 (Actin Related Protein 2/3 Complex, Subunit 3, 21kDa (ARPC3))
    Binding Specificity
    • 16
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2-175
    Reactivity
    • 40
    • 25
    • 18
    • 7
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 37
    • 2
    • 1
    Rabbit
    Clonality
    • 38
    • 2
    Polyclonal
    Conjugate
    • 20
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ARPC3 antibody is un-conjugated
    Application
    • 36
    • 14
    • 13
    • 13
    • 12
    • 8
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Actin-related protein 2/3 complex subunit 3 protein (2-175AA)
    Isotype
    IgG
  • Application Notes
    Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    ARPC3 (Actin Related Protein 2/3 Complex, Subunit 3, 21kDa (ARPC3))
    Alternative Name
    ARPC3 (ARPC3 Products)
    Synonyms
    ARC21 antibody, p21-Arc antibody, 1110006A04Rik antibody, 21kDa antibody, AA408672 antibody, AI788639 antibody, p21-Ar antibody, p21Arc antibody, arc21 antibody, p21-arc antibody, zgc:86828 antibody, actin related protein 2/3 complex subunit 3 antibody, actin related protein 2/3 complex, subunit 3 antibody, actin related protein 2/3 complex subunit 3 L homeolog antibody, actin related protein 2/3 complex, subunit 3, 21kDa antibody, actin related protein 2/3 complex subunit 3 pseudogene antibody, actin-related protein 2/3 complex subunit 3 antibody, actin-related protein 2/3 complex subunit 3 pseudogene antibody, ARPC3 antibody, Arpc3 antibody, arpc3.L antibody, LOC738738 antibody, arpc3 antibody, LOC100036831 antibody, LOC100341254 antibody
    Background

    Background: Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9230079). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:9230079). In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (PubMed:29925947). The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs) (PubMed:29925947).

    Aliases: ARPC3 antibody, ARC21Actin-related protein 2/3 complex subunit 3 antibody, Arp2/3 complex 21 kDa subunit antibody, p21-ARC antibody

    UniProt
    O15145
    Pathways
    RTK Signaling, Regulation of Actin Filament Polymerization
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