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SERF2 antibody (AA 107-224)

SERF2 Reactivity: Human ELISA, WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7152338
  • Target See all SERF2 Antibodies
    SERF2 (Small EDRK-Rich Factor 2 (SERF2))
    Binding Specificity
    • 3
    • 1
    AA 107-224
    Reactivity
    • 12
    • 9
    • 1
    Human
    Host
    • 12
    Rabbit
    Clonality
    • 12
    Polyclonal
    Conjugate
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SERF2 antibody is un-conjugated
    Application
    • 4
    • 2
    • 2
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Extracellular serine/threonine protein kinase FAM20C protein (107-224AA)
    Isotype
    IgG
  • Application Notes
    Recommended dilution: WB:1:500-1:5000, IHC:1:500-1:1000,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    SERF2 (Small EDRK-Rich Factor 2 (SERF2))
    Alternative Name
    FAM2C (SERF2 Products)
    Synonyms
    4F5REL antibody, FAM2C antibody, H4F5REL antibody, HsT17089 antibody, C80083 antibody, Msmac1l antibody, m4F5rel antibody, small EDRK-rich factor 2 antibody, SERF2 antibody, Serf2 antibody
    Background

    Background: Golgi serine/threonine protein kinase that phosphorylates secretory pathway proteins within Ser-x-Glu/pSer motifs and plays a key role in biomineralization of bones and teeth (PubMed:22582013, PubMed:23754375, PubMed:25789606). Constitutes the main protein kinase for extracellular proteins, generating the majority of the extracellular phosphoproteome (PubMed:26091039). Mainly phosphorylates proteins within the Ser-x-Glu/pSer motif, but also displays a broader substrate specificity (PubMed:26091039). Phosphorylates casein as well as a number of proteins involved in biomineralization such as AMELX, AMTN, ENAM and SPP1 (PubMed:22582013, PubMed:25789606). In addition to its role in biomineralization, also plays a role in lipid homeostasis, wound healing and cell migration and adhesion (PubMed:26091039).

    Aliases: C76981 antibody, Dentin matrix protein 4 antibody, DKFZp547C074 antibody, DMP-4 antibody, DMP4 antibody, DMP4_HUMAN antibody, Extracellular serine/threonine protein kinase Fam20C antibody, Fam20c antibody, Family with sequence similarity 20 member C antibody, GEF CK antibody, Golgi enriched fraction casein kinase antibody, Protein FAM20C antibody, RNS antibody

    UniProt
    Q8IXL6
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