ABCA7 antibody (Middle Region)
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- Target See all ABCA7 Antibodies
- ABCA7 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 7 (ABCA7))
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Binding Specificity
- Middle Region
- Reactivity
- Human, Mouse, Rat, Cow, Dog, Guinea Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ABCA7 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- DTQTRHLSGG MQRKLSVAIA FVGGSRVVIM DEPTAGVDPA SRRGIWELLL
- Predicted Reactivity
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 93%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against Abca7. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide corresponding to a region of Mouse
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 2159 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Genetic Variations in ABCA7 Can Increase Secreted Levels of Amyloid-β40 and Amyloid-β42 Peptides and ABCA7 Transcription in Cell Culture Models." in: Journal of Alzheimer's disease : JAD, Vol. 53, Issue 3, pp. 875-92, (2016) (PubMed).
: "
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Genetic Variations in ABCA7 Can Increase Secreted Levels of Amyloid-β40 and Amyloid-β42 Peptides and ABCA7 Transcription in Cell Culture Models." in: Journal of Alzheimer's disease : JAD, Vol. 53, Issue 3, pp. 875-92, (2016) (PubMed).
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- Target
- ABCA7 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 7 (ABCA7))
- Alternative Name
- Abca7 (ABCA7 Products)
- Synonyms
- ABCX antibody, Abc51 antibody, ABCA-SSN antibody, ABCA7 antibody, ATP-binding cassette, sub-family A (ABC1), member 7 antibody, ATP binding cassette subfamily A member 7 antibody, ATP-binding cassette sub-family A member 7 antibody, Abca7 antibody, ABCA7 antibody, LOC100088822 antibody
- Background
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Abca7 plays a role in phagocytosis by macrophages of apoptotic cells.Abca7 binds APOA1 and may function in apolipoprotein-mediated phospholipid efflux from cells. Abca7 may also mediate cholesterol efflux. Abca7 may regulate cellular ceramide homeostasis during keratinocytes differentiation.
Alias Symbols: ABCX, Abc51
Protein Size: 2159 - Molecular Weight
- 237 kDa
- Gene ID
- 27403
- NCBI Accession
- NM_013850, NP_038878
- UniProt
- Q91V24
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