IRF9 antibody
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- Target See all IRF9 Antibodies
- IRF9 (Interferon Regulatory Factor 9 (IRF9))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This IRF9 antibody is un-conjugated
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Application
- Immunofluorescence (IF), Flow Cytometry (FACS)
- Specificity
- Transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
- Cross-Reactivity (Details)
- Human
- Purification
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
- Immunogen
- Recombinant full-length human IRF9 protein
- Isotype
- IgG2a
- Top Product
- Discover our top product IRF9 Primary Antibody
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anti-Interferon Regulatory Factor 9 (IRF9) (AA 75-104) antibody
IRF9 Reactivity: Human, Mouse WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Interferon Regulatory Factor 9 (IRF9) (AA 75-104) antibodyIRF9 Reactivity: Human, Mouse WB, IF, IHC (p) Host: Rabbit Polyclonal RB19229 unconjugated
anti-Interferon Regulatory Factor 9 (IRF9) (AA 1-393) antibodyIRF9 Reactivity: Human WB, ELISA, IHC (p) Host: Mouse Monoclonal 1C10 unconjugated
anti-Interferon Regulatory Factor 9 (IRF9) (AA 101-200) antibodyIRF9 Reactivity: Human WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC Host: Rabbit Polyclonal unconjugated
anti-Interferon Regulatory Factor 9 (IRF9) antibodyIRF9 Reactivity: Human, Mouse WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Interferon Regulatory Factor 9 (IRF9) (AA 1-393) antibodyIRF9 Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
anti-Interferon Regulatory Factor 9 (IRF9) (AA 171-393) antibodyIRF9 Reactivity: Human WB, IHC, IF, IHC (p), ICC Host: Rabbit Polyclonal unconjugated
anti-Interferon Regulatory Factor 9 (IRF9) (AA 44-180) antibodyIRF9 Reactivity: Human WB, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-Interferon Regulatory Factor 9 (IRF9) (AA 1-393) antibodyIRF9 Reactivity: Human WB, IF Host: Mouse Polyclonal unconjugated
anti-Interferon Regulatory Factor 9 (IRF9) (AA 1-394) antibodyIRF9 Reactivity: Human WB, ELISA, IHC, IHC (p) Host: Mouse Monoclonal 1C10 unconjugated
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- Application Notes
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Positive Control: MCF-7, Jurkat or K562 cells.
Known Application: Flow Cytometry (1-2 μg/million cells), ,Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
- Restrictions
- For Research Use only
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- Concentration
- 200 μg/mL
- Buffer
- Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-80 °C
- Storage Comment
- Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.
- Expiry Date
- 24 months
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- Target
- IRF9 (Interferon Regulatory Factor 9 (IRF9))
- Alternative Name
- IRF9 (IRF9 Products)
- Synonyms
- IRF-9 antibody, ISGF3 antibody, ISGF3G antibody, p48 antibody, zgc:92097 antibody, Irf-9 antibody, Isgf3g antibody, interferon regulatory factor 9 antibody, IRF9 antibody, irf9 antibody, Irf9 antibody
- Background
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IFN alpha responsive transcription factor subunit, Interferon regulatory factor 9, Interferon-stimulated gene factor 3 gamma, interferon-stimulated transcription factor 3, gamma 48 kDa, IRF-9, ISGF-3 gamma, ISGF3 p48 subunit, ISGF3G, p48, Transcriptional regulator ISGF3 subunit gamma,Interferon regulatory factor 9 / IRF-9
Cellular localisation: Cytoplasm. Nucleus. Translocated into the nucleus upon activation by IFN-alpha/beta. - Molecular Weight
- 43.34kDa
- Gene ID
- 10379, 1706
- UniProt
- Q00978
- Pathways
- JAK-STAT Signaling, Interferon-gamma Pathway, Hepatitis C
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