TXNRD2 antibody (AA 100-310)
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- Target See all TXNRD2 Antibodies
- TXNRD2 (Thioredoxin Reductase 2 (TXNRD2))
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Binding Specificity
- AA 100-310
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TXNRD2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Sequence
- AALLGGLIQD APNYGWEVAQ PVPHDWRKMA EAVQNHVKSL NWGHRVQLQD RKVKYFNIKA SFVDEHTVCG VAKGGKEILL SADHIIIATG GRPRYPTHIE GALEYGITSD DIFWLKESPG KTLVVGASYV ALECAGFLTG IGLDTTIMMR SIPLRGFDQQ MSSMVIEHMA SHGTRFLRGC APSRVRRLPD GQLQVTWEDS TTGKEDTGTF D
- Cross-Reactivity
- Human, Mouse
- Characteristics
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 100-310 of human Thioredoxin reductase 2 (Thioredoxin reductase 2 (TXNRD2 ) ) (NP_006431.2).
- Isotype
- IgG
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anti-Thioredoxin Reductase 2 (TXNRD2) (AA 100-310) antibody
TXNRD2 Reactivity: Human WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Thioredoxin Reductase 2 (TXNRD2) (C-Term) antibodyTXNRD2 Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Thioredoxin Reductase 2 (TXNRD2) (C-Term) antibodyTXNRD2 Reactivity: Human WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Thioredoxin Reductase 2 (TXNRD2) (C-Term) antibodyTXNRD2 Reactivity: Human, Mouse, Rat WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Thioredoxin Reductase 2 (TXNRD2) antibodyTXNRD2 Reactivity: Human WB Host: Rabbit Monoclonal unconjugated
anti-Thioredoxin Reductase 2 (TXNRD2) (C-Term) antibodyTXNRD2 Reactivity: Human, Rat, Monkey WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Thioredoxin Reductase 2 (TXNRD2) (AA 471-520) antibodyTXNRD2 Reactivity: Human, Mouse, Rat WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
- Comment
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- TXNRD2 (Thioredoxin Reductase 2 (TXNRD2))
- Alternative Name
- TXNRD2 (TXNRD2 Products)
- Synonyms
- CG11401 antibody, Dm-TrxR antibody, DmTrx antibody, DmTrxR-2 antibody, Dmel\\CG11401 antibody, Trxr2 antibody, trxr-2 antibody, SELZ antibody, TR antibody, TR-BETA antibody, TR3 antibody, TRXR2 antibody, AA118373 antibody, ESTM573010 antibody, TGR antibody, Tr3 antibody, Trxrd2 antibody, thioredoxin reductase 2 antibody, Trxr-2 antibody, TXNRD2 antibody, Txnrd2 antibody
- Background
- The protein encoded by this gene belongs to the pyridine nucleotide-disulfide oxidoreductase family, and is a member of the thioredoxin (Trx) system. Three thioredoxin reductase (TrxR) isozymes are found in mammals. TrxRs are selenocysteine-containing flavoenzymes, which reduce thioredoxins, as well as other substrates, and play a key role in redox homoeostasis. This gene encodes a mitochondrial form important for scavenging reactive oxygen species in mitochondria. It functions as a homodimer containing FAD, and selenocysteine (Sec) at the active site. Sec is encoded by UGA codon that normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element, which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternatively spliced transcript variants encoding different isoforms, including a few localized in the cytosol and some lacking the C-terminal Sec residue, have been found for this gene.,TXNRD2,SELZ,TR,TR-BETA,TR3,TRXR2,Cell Biology & Developmental Biology,Endocrine & Metabolism,TXNRD2
- Molecular Weight
- 30 kDa/46 kDa/53 kDa/56 kDa
- Gene ID
- 10587
- UniProt
- Q9NNW7
- Pathways
- Cell RedoxHomeostasis
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