Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Buffer
In 1x PBS, pH 7.4
Handling Advice
Aliquot to avoid repeated freezing and thawing.
Storage
-20 °C
Storage Comment
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Seeßle, Liebisch, Schmitz, Stremmel, Chamulitrat: "Palmitate activation by fatty acid transport protein 4 as a model system for hepatocellular apoptosis and steatosis." in: Biochimica et biophysica acta, Vol. 1851, Issue 5, pp. 549-65, (2015) (PubMed).
OTierney-Ginn, Roberts, Gillingham, Walker, Glazebrook, Thornburg, Grove, Frias: "Influence of high fat diet and resveratrol supplementation on placental fatty acid uptake in the Japanese macaque." in: Placenta, Vol. 36, Issue 8, pp. 903-10, (2015) (PubMed).
Stremmel, Staffer, Wannhoff, Pathil, Chamulitrat: "Plasma membrane phospholipase A2 controls hepatocellular fatty acid uptake and is responsive to pharmacological modulation: implications for nonalcoholic steatohepatitis." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 28, Issue 7, pp. 3159-70, (2014) (PubMed).
Li, Vahlquist, Törmä: "Interactions between FATP4 and ichthyin in epidermal lipid processing may provide clues to the pathogenesis of autosomal recessive congenital ichthyosis." in: Journal of dermatological science, Vol. 69, Issue 3, pp. 195-201, (2013) (PubMed).
Dubé, Gravel, Martin, Desparois, Moussa, Ethier-Chiasson, Forest, Giguère, Masse, Lafond: "Modulation of fatty acid transport and metabolism by maternal obesity in the human full-term placenta." in: Biology of reproduction, Vol. 87, Issue 1, pp. 14, 1-11, (2012) (PubMed).
Taube, Lambernd, van Echten-Deckert, Eckardt, Eckel: "Adipokines promote lipotoxicity in human skeletal muscle cells." in: Archives of physiology and biochemistry, Vol. 118, Issue 3, pp. 92-101, (2012) (PubMed).
Klar, Schweiger, Zimmerman, Zechner, Li, Törmä, Vahlquist, Bouadjar, Dahl, Fischer: "Mutations in the fatty acid transport protein 4 gene cause the ichthyosis prematurity syndrome." in: American journal of human genetics, Vol. 85, Issue 2, pp. 248-53, (2009) (PubMed).
Sandoval, Fraisl, Arias-Barrau, Dirusso, Singer, Sealls, Black: "Fatty acid transport and activation and the expression patterns of genes involved in fatty acid trafficking." in: Archives of biochemistry and biophysics, Vol. 477, Issue 2, pp. 363-71, (2008) (PubMed).
Target
SLC27A4
(Solute Carrier Family 27 (Fatty Acid Transporter), Member 4 (SLC27A4))