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MYSM1 antibody

MYSM1 Reactivity: Human, Mouse ELISA, WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7242539
  • Target See all MYSM1 Antibodies
    MYSM1 (Myb-Like, SWIRM and MPN Domains 1 (MYSM1))
    Reactivity
    • 34
    • 17
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 34
    Rabbit
    Clonality
    • 34
    Polyclonal
    Conjugate
    • 13
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MYSM1 antibody is un-conjugated
    Application
    • 21
    • 20
    • 14
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Synthetic peptide of human MYSM1
    Isotype
    IgG
  • Application Notes
    WB 1:500-1:2000, IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.7 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    MYSM1 (Myb-Like, SWIRM and MPN Domains 1 (MYSM1))
    Alternative Name
    MYSM1 (MYSM1 Products)
    Synonyms
    2A-DUB antibody, 2ADUB antibody, RP4-592A1.1 antibody, C130067A03Rik antibody, C530050H10Rik antibody, RGD1311787 antibody, 2adub antibody, Myb like, SWIRM and MPN domains 1 antibody, myb-like, SWIRM and MPN domains 1 antibody, Myb like, SWIRM and MPN domains 1 L homeolog antibody, MYSM1 antibody, Mysm1 antibody, mysm1.L antibody
    Background
    Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.
    Molecular Weight
    95 kDa
    NCBI Accession
    NP_001078956
    UniProt
    Q5VVJ2
    Pathways
    Chromatin Binding
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