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FCHO2 antibody (AA 100-203)

FCHO2 Reactivity: Human WB, ELISA, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7152394
  • Target See all FCHO2 Antibodies
    FCHO2 (FCH Domain Only 2 (FCHO2))
    Binding Specificity
    • 7
    • 6
    • 6
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 100-203
    Reactivity
    • 25
    • 12
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 25
    Rabbit
    Clonality
    • 25
    Polyclonal
    Conjugate
    • 11
    • 4
    • 3
    • 3
    • 2
    • 2
    This FCHO2 antibody is un-conjugated
    Application
    • 21
    • 17
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    Cross-Reactivity
    Human, Mouse
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human F-BAR domain only protein 2 protein (100-203AA)
    Isotype
    IgG
  • Application Notes
    Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    FCHO2 (FCH Domain Only 2 (FCHO2))
    Alternative Name
    FCHO2 (FCHO2 Products)
    Synonyms
    5832424M12Rik antibody, AA387320 antibody, RGD1565396 antibody, cb304 antibody, sb:cb304 antibody, wu:fa01a02 antibody, zgc:112167 antibody, FCH domain only 2 antibody, FCHO2 antibody, fcho2 antibody, Fcho2 antibody
    Background

    Background: Functions in an early step of clathrin-mediated endocytosis. Has both a membrane binding/bending activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. Has a lipid-binding activity with a preference for membranes enriched in phosphatidylserine and phosphoinositides (Pi(4,5) biphosphate) like the plasma membrane. Its membrane-bending activity might be important for the subsequent action of clathrin and adaptors in the formation of clathrin-coated vesicles. Involved in adaptor protein complex AP-2-dependent endocytosis of the transferin receptor, it also functions in the AP-2-independent endocytosis of the LDL receptor.

    Aliases: FCHO2F-BAR domain only protein 2 antibody

    UniProt
    Q0JRZ9
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