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Desmoglein 2 antibody (AA 72-121)

DSG2 Reactivity: Human, Rat, Mouse, Monkey WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6744433
  • Target See all Desmoglein 2 (DSG2) Antibodies
    Desmoglein 2 (DSG2)
    Binding Specificity
    • 15
    • 14
    • 8
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 72-121
    Reactivity
    • 89
    • 36
    • 33
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    Human, Rat, Mouse, Monkey
    Host
    • 71
    • 18
    Rabbit
    Clonality
    • 62
    • 27
    Polyclonal
    Conjugate
    • 42
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Desmoglein 2 antibody is un-conjugated
    Application
    • 76
    • 26
    • 21
    • 18
    • 16
    • 13
    • 13
    • 12
    • 10
    • 6
    • 6
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Brand
    IHC-plus™
    Specificity
    Human DSG2
    Predicted Reactivity
    Percent identity by BLAST analysis: Human, Mouse, Rat (100%) Bovine, Rabbit, Horse, Guinea pig (92%).
    Purification
    Immunoaffinity purified
    Immunogen
    Synthetic peptide located between aa72-121 of human DSG2 (Q14126, NP_001934). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat (100%), Elephant, Bovine, Rabbit, Horse, Guinea pig (92%), Bat (85%), Opossum (84%).

    Type of Immunogen: Synthetic peptide
    Isotype
    IgG
    Top Product
    Discover our top product DSG2 Primary Antibody
  • Application Notes
    Approved: IHC, IHC-P (5 μg/mL), WB (1 μg/mL)

    Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL. Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as second antibody. ELISA titer in peptide based assay: 1:1562500.
    Comment

    Target Species of Antibody: Human

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Distilled water
    Concentration
    Lot specific
    Buffer
    Lyophilized from PBS with 2 % sucrose
    Handling Advice
    Avoid repeat freeze-thaw cycles.
    Storage
    4 °C,-20 °C
    Storage Comment
    Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
    Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
  • Target
    Desmoglein 2 (DSG2)
    Alternative Name
    DSG2 / Desmoglein 2 (DSG2 Products)
    Synonyms
    DSG2 antibody, dsc antibody, dsga antibody, si:dkeyp-51f12.6 antibody, wu:fj23f02 antibody, ARVC10 antibody, ARVD10 antibody, CDHF5 antibody, CMD1BB antibody, HDGC antibody, AA408168 antibody, D18Ertd293e antibody, desmoglein 2 antibody, desmoglein 2, tandem duplicate 1 antibody, DSG2 antibody, dsg2.1 antibody, dsg2 antibody, Dsg2 antibody
    Background
    Name/Gene ID: DSG2
    Family: Cadherin

    Synonyms: DSG2, ARVC10, Cadherin family member 5, CDHF5, CMD1BB, Desmoglein-2, Desmoglein II, HDGC, ARVD10, Desmoglein 2
    Gene ID
    1829
    NCBI Accession
    NP_001934
    UniProt
    Q14126
    Pathways
    Cell-Cell Junction Organization
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