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GTF2H1 antibody (N-Term)

GTF2H1 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, ICC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6256996
  • Target See all GTF2H1 Antibodies
    GTF2H1 (General Transcription Factor IIH, Polypeptide 1, 62kDa (GTF2H1))
    Binding Specificity
    • 15
    • 14
    • 8
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 47
    • 29
    • 8
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Mouse, Rat
    Host
    • 51
    • 7
    Rabbit
    Clonality
    • 52
    • 6
    Polyclonal
    Conjugate
    • 27
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This GTF2H1 antibody is un-conjugated
    Application
    • 49
    • 23
    • 13
    • 13
    • 8
    • 5
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificity
    TF2H1 Antibody detects endogenous levels of total TF2H1.
    Predicted Reactivity
    Pig,Zebrafish,Bovine,Horse,Sheep,Dog,Chicken,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human TF2H1, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product GTF2H1 Primary Antibody
  • Application Notes
    WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    GTF2H1 (General Transcription Factor IIH, Polypeptide 1, 62kDa (GTF2H1))
    Alternative Name
    GTF2H1 (GTF2H1 Products)
    Synonyms
    62kDa antibody, AW743425 antibody, AW822074 antibody, BTF2 p62 antibody, C77871 antibody, p62 antibody, GTF2H1 antibody, BTF2 antibody, P62 antibody, TFB1 antibody, TFIIH antibody, gtf2h1 antibody, MGC53309 antibody, btf2 antibody, tfiih antibody, CG8151 antibody, Dmel\\CG8151 antibody, Dmp62 antibody, TfBl antibody, l(2)06949 antibody, l(2)06950 antibody, zgc:92126 antibody, general transcription factor IIH subunit 1 antibody, general transcription factor II H, polypeptide 1 antibody, general transcription factor IIH subunit 1 L homeolog antibody, Transcription factor B1 antibody, general transcription factor IIH, polypeptide 1 antibody, GTF2H1 antibody, Gtf2h1 antibody, gtf2h1.L antibody, gtf2h1 antibody, Tfb1 antibody
    Background

    Description: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.

    Gene: GTF2H1

    Molecular Weight
    57 kDa
    Gene ID
    2965
    UniProt
    P32780
    Pathways
    DNA Damage Repair
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