GTF2H1 antibody (N-Term)
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- Target See all GTF2H1 Antibodies
- GTF2H1 (General Transcription Factor IIH, Polypeptide 1, 62kDa (GTF2H1))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GTF2H1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
- Specificity
- TF2H1 Antibody detects endogenous levels of total TF2H1.
- Predicted Reactivity
- Pig,Zebrafish,Bovine,Horse,Sheep,Dog,Chicken,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human TF2H1, corresponding to a region within N-terminal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product GTF2H1 Primary Antibody
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- Application Notes
- WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- GTF2H1 (General Transcription Factor IIH, Polypeptide 1, 62kDa (GTF2H1))
- Alternative Name
- GTF2H1 (GTF2H1 Products)
- Synonyms
- 62kDa antibody, AW743425 antibody, AW822074 antibody, BTF2 p62 antibody, C77871 antibody, p62 antibody, GTF2H1 antibody, BTF2 antibody, P62 antibody, TFB1 antibody, TFIIH antibody, gtf2h1 antibody, MGC53309 antibody, btf2 antibody, tfiih antibody, CG8151 antibody, Dmel\\CG8151 antibody, Dmp62 antibody, TfBl antibody, l(2)06949 antibody, l(2)06950 antibody, zgc:92126 antibody, general transcription factor IIH subunit 1 antibody, general transcription factor II H, polypeptide 1 antibody, general transcription factor IIH subunit 1 L homeolog antibody, Transcription factor B1 antibody, general transcription factor IIH, polypeptide 1 antibody, GTF2H1 antibody, Gtf2h1 antibody, gtf2h1.L antibody, gtf2h1 antibody, Tfb1 antibody
- Background
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Description: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.
Gene: GTF2H1
- Molecular Weight
- 57 kDa
- Gene ID
- 2965
- UniProt
- P32780
- Pathways
- DNA Damage Repair
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