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SLC38A9 antibody (AA 1-119)

SLC38A9 Reactivity: Human ELISA, WB, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7169972
  • Target See all SLC38A9 Antibodies
    SLC38A9 (Solute Carrier Family 38, Member 9 (SLC38A9))
    Binding Specificity
    • 4
    • 1
    AA 1-119
    Reactivity
    • 5
    • 1
    • 1
    • 1
    Human
    Host
    • 5
    Rabbit
    Clonality
    • 5
    Polyclonal
    Conjugate
    • 2
    • 1
    • 1
    • 1
    This SLC38A9 antibody is un-conjugated
    Application
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Sodium-coupled neutral amino acid transporter 9 protein (1-119AA)
    Isotype
    IgG
  • Application Notes
    Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    SLC38A9 (Solute Carrier Family 38, Member 9 (SLC38A9))
    Alternative Name
    SLC38A9 (SLC38A9 Products)
    Synonyms
    MGC81406 antibody, 4833412L08Rik antibody, 6720411P22Rik antibody, 9130023D20Rik antibody, 9430067K09Rik antibody, A730092C09 antibody, RGD1311881 antibody, solute carrier family 38 member 9 antibody, solute carrier family 38 member 9 L homeolog antibody, solute carrier family 38, member 9 antibody, SLC38A9 antibody, slc38a9.L antibody, slc38a9 antibody, Slc38a9 antibody
    Background

    Background: Lysosomal amino acid transporter involved in the activation of mTORC1 in response to amino acids. Probably acts as an amino acid sensor of the Rag GTPases and Ragulator complexes, 2 complexes involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids (PubMed:25561175, PubMed:25567906). Following activation by amino acids, the Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. SLC38A9 mediates transport of amino acids with low capacity and specificity with a slight preference for polar amino acids, suggesting that it acts as an amino acid sensor instead (PubMed:25561175, PubMed:25567906). The high concentration of arginine in lysosomes suggests that it acts as an arginine sensor (PubMed:25567906).

    Aliases: FLJ46104 antibody, FLJ90709 antibody, Homo sapiens solute carrier family 38, member 9 antibody, MGC120544 antibody, OTTHUMP00000161835 antibody, Putative sodium coupled neutral amino acid transporter 9 antibody, Putative sodium-coupled neutral amino acid transporter 9 antibody, Putative uncharacterized protein FLJ90709 antibody, S38A9_HUMAN antibody, SLC38A9 antibody

    UniProt
    Q8NBW4
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