This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This EID2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 177-208 amino acids from the C-terminal region of human EID2.
EID2 interacts with EP300 and acts as a repressor of MYOD-dependent transcription and muscle differentiation. Inhibits EP300 histone acetyltransferase activity. Acts as a repressor of TGFB/SMAD transcriptional responses. It may act as a repressor of the TGFB/SMAD3-dependent signaling by selectively blocking formation of TGFB-induced SMAD3-SMAD4 complex.