SNAPIN antibody (N-Term)
-
- Target See all SNAPIN Antibodies
- SNAPIN (SNAP-Associated Protein (SNAPIN))
-
Binding Specificity
- N-Term
-
Reactivity
- Human, Mouse, Rat
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This SNAPIN antibody is un-conjugated
-
Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Specificity
- SNAPIN Antibody detects endogenous levels of total SNAPIN.
- Predicted Reactivity
- Pig,Bovine,Horse,Rabbit,Dog
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human SNAPIN, corresponding to a region within N-terminal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product SNAPIN Primary Antibody
-
anti-SNAP-Associated Protein (SNAPIN) (AA 41-136) antibody
SNAPIN Reactivity: Human WB, ELISA, IHC (p) Host: Mouse Monoclonal 3H1 unconjugated
anti-SNAP-Associated Protein (SNAPIN) (AA 2-136) antibodySNAPIN Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-SNAP-Associated Protein (SNAPIN) (AA 41-136) antibodySNAPIN Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated
anti-SNAP-Associated Protein (SNAPIN) (AA 1-136) antibodySNAPIN Reactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-SNAP-Associated Protein (SNAPIN) (AA 117-136), (C-Term) antibodySNAPIN Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
-
- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
-
- Target
- SNAPIN (SNAP-Associated Protein (SNAPIN))
- Alternative Name
- SNAPIN (SNAPIN Products)
- Synonyms
- SNAPAP antibody, si:dkey-222b8.2 antibody, SNAPIN antibody, BLOC1S7 antibody, BLOS7 antibody, 25kDa antibody, AA407989 antibody, AV026596 antibody, Bloc1s7 antibody, Snap25bp antibody, Snapap antibody, SNAP associated protein antibody, SNAP-associated protein L homeolog antibody, SNAP-associated protein antibody, SNAPIN antibody, snapin.L antibody, snapin antibody, Snapin antibody
- Background
-
Description: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling. May modulate a step between vesicle priming, fusion and calcium-dependent neurotransmitter release through its ability to potentiate the interaction of synaptotagmin with the SNAREs and the plasma-membrane-associated protein SNAP25. Its phosphorylation state influences exocytotic protein interactions and may regulate synaptic vesicle exocytosis. May also have a role in the mechanisms of SNARE-mediated membrane fusion in non-neuronal cells (PubMed:17182842, PubMed:18167355). As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor (PubMed:25898167).
Gene: SNAPIN
- Molecular Weight
- 15-18 kDa
- Gene ID
- 23557
- UniProt
- O95295
- Pathways
- Synaptic Membrane, Synaptic Vesicle Exocytosis
-
