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TGM3 antibody (AA 601-693)

TGM3 Reactivity: Mouse, Rat ELISA, IF (cc), IF (p), IHC (fro), IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN736253
  • Target See all TGM3 Antibodies
    TGM3 (Transglutaminase 3 (E Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM3))
    Binding Specificity
    • 14
    • 8
    • 7
    • 6
    • 5
    • 1
    • 1
    • 1
    AA 601-693
    Reactivity
    • 36
    • 22
    • 15
    • 1
    • 1
    • 1
    Mouse, Rat
    Host
    • 50
    • 4
    • 1
    • 1
    Rabbit
    Clonality
    • 52
    • 4
    Polyclonal
    Conjugate
    • 18
    • 9
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TGM3 antibody is un-conjugated
    Application
    • 35
    • 21
    • 12
    • 12
    • 12
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Mouse, Rat
    Predicted Reactivity
    Human,Dog,Cow,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human TGM3
    Isotype
    IgG
    Top Product
    Discover our top product TGM3 Primary Antibody
  • Application Notes
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Kawabe, Takano, Moriyama, Nakamura: "Transglutaminases Derived from Astrocytes Accelerate Amyloid β Aggregation." in: Neurochemical research, Vol. 42, Issue 8, pp. 2384-2391, (2017) (PubMed).

  • Target
    TGM3 (Transglutaminase 3 (E Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM3))
    Alternative Name
    TGM3 (TGM3 Products)
    Synonyms
    TGE antibody, TG(E) antibody, AI893889 antibody, RGD1561831 antibody, transglutaminase 3 antibody, transglutaminase 3, E polypeptide antibody, TGM3 antibody, Tgm3 antibody
    Background

    Synonyms: TGE, Protein-glutamine gamma-glutamyltransferase E, Transglutaminase E, TG(E), TGase E, Transglutaminase-3, TGase-3, TGM3

    Background: Catalyzes the calcium-dependent formation of isopeptide cross-links between glutamine and lysine residues in various proteins, as well as the conjugation of polyamines to proteins. Involved in the formation of the cornified envelope (CE), a specialized component consisting of covalent cross-links of proteins beneath the plasma membrane of terminally differentiated keratinocytes. Catalyzes small proline-rich proteins (SPRR1 and SPRR2) and LOR cross-linking to form small interchain oligomers, which are further cross-linked by TGM1 onto the growing CE scaffold (By similarity). In hair follicles, involved in cross-linking structural proteins to hardening the inner root sheath.

    Gene ID
    7053
    UniProt
    Q08188
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