FERMT2 antibody (C-Term)
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- Target See all FERMT2 Antibodies
- FERMT2 (Fermitin Family Member 2 (FERMT2))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This FERMT2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Specificity
- Kindlin 2 Antibody detects endogenous levels of total Kindlin 2.
- Predicted Reactivity
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human Kindlin 2, corresponding to a region within C-terminal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product FERMT2 Primary Antibody
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anti-Fermitin Family Member 2 (FERMT2) antibody
FERMT2 Reactivity: Human, Rat, Dog, Monkey WB, IHC, IF, IP, IHC (p) Host: Mouse Monoclonal 14A11 unconjugated
anti-Fermitin Family Member 2 (FERMT2) (AA 1-680) antibodyFERMT2 Reactivity: Human WB, ELISA, IF Host: Mouse Monoclonal 2G11 unconjugated
anti-Fermitin Family Member 2 (FERMT2) (AA 155-232) antibodyFERMT2 Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Fermitin Family Member 2 (FERMT2) (AA 380-550) antibodyFERMT2 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Fermitin Family Member 2 (FERMT2) (AA 641-669), (C-Term) antibodyFERMT2 Reactivity: Human WB Host: Rabbit Polyclonal RB39207 unconjugated
anti-Fermitin Family Member 2 (FERMT2) (AA 402-451) antibodyFERMT2 Reactivity: Human, Cow, Pig, Rabbit WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- FERMT2 (Fermitin Family Member 2 (FERMT2))
- Alternative Name
- FERMT2 (FERMT2 Products)
- Synonyms
- AA960555 antibody, Kindlin-2 antibody, Mig2 antibody, Plekhc1 antibody, KIND2 antibody, MIG2 antibody, PLEKHC1 antibody, UNC112 antibody, UNC112B antibody, mig-2 antibody, fermitin family member 2 antibody, Fermt2 antibody, FERMT2 antibody
- Background
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Description: Scaffolding protein that enhances integrin activation mediated by TLN1 and/or TLN2, but activates integrins only weakly by itself. Binds to membranes enriched in phosphoinositides. Enhances integrin-mediated cell adhesion onto the extracellular matrix and cell spreading, this requires both its ability to interact with integrins and with phospholipid membranes. Required for the assembly of focal adhesions. Participates in the connection between extracellular matrix adhesion sites and the actin cytoskeleton and also in the orchestration of actin assembly and cell shape modulation. Recruits FBLIM1 to focal adhesions. Plays a role in the TGFB1 and integrin signaling pathways. Stabilizes active CTNNB1 and plays a role in the regulation of transcription mediated by CTNNB1 and TCF7L2/TCF4 and in Wnt signaling.
Gene: FERMT2
- Molecular Weight
- 78 kDa
- Gene ID
- 10979
- UniProt
- Q96AC1
- Pathways
- Cell-Cell Junction Organization
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