PPM1E antibody (Internal Region)
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- Target See all PPM1E Antibodies
- PPM1E (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1E (PPM1E))
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Binding Specificity
- Internal Region
- Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PPM1E antibody is un-conjugated
- Application
- ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
- Specificity
- PPM1E Antibody detects endogenous levels of total PPM1E.
- Predicted Reactivity
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human PPM1E, corresponding to a region within the internal amino acids.
- Isotype
- IgG
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- Application Notes
- WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- PPM1E (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1E (PPM1E))
- Alternative Name
- PPM1E (PPM1E Products)
- Synonyms
- AW049266 antibody, B930008A12Rik antibody, POPX1 antibody, PP2CH antibody, mKIAA1072 antibody, CaMKP-N antibody, caMKN antibody, protein phosphatase 1E (PP2C domain containing) antibody, protein phosphatase, Mg2+/Mn2+ dependent 1E antibody, protein phosphatase, Mg2+/Mn2+ dependent, 1E antibody, Ppm1e antibody, PPM1E antibody
- Background
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Description: Protein phosphatase that inactivates multifunctional CaM kinases such as CAMK4 and CAMK2 (By similarity). Dephosphorylates and inactivates PAK. May play a role in the inhibition of actin fiber stress breakdown and in morphological changes driven by TNK2/CDC42. Dephosphorylates PRKAA2 (By similarity).
Gene: PPM1E
- Molecular Weight
- 85 kDa
- Gene ID
- 22843
- UniProt
- Q8WY54
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