MAVS antibody (C-Term)
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- Target See all MAVS Antibodies
- MAVS (Mitochondrial Antiviral Signaling Protein (MAVS))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MAVS antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- VISA Antibody detects endogenous levels of total VISA.
- Predicted Reactivity
- Chicken
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human VISA, corresponding to a region within C-terminal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product MAVS Primary Antibody
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anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 1-65) antibody
MAVS Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 34-96) antibodyMAVS Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 1-30), (N-Term) antibodyMAVS Reactivity: Mouse WB Host: Rabbit Polyclonal RB42373 unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 160-450) antibodyMAVS Reactivity: Human WB, IHC, IP, ICC Host: Mouse Monoclonal Adri-1 unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 1-540) antibodyMAVS Reactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (N-Term) antibodyMAVS Reactivity: Human, Mouse, Cow WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 477-505), (C-Term) antibodyMAVS Reactivity: Human WB Host: Rabbit Polyclonal RB33921 unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 160-450) antibodyMAVS Reactivity: Human WB, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 470-519) antibodyMAVS Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 146-195) antibodyMAVS Reactivity: Human, Mouse, Cow WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- MAVS (Mitochondrial Antiviral Signaling Protein (MAVS))
- Alternative Name
- MAVS (MAVS Products)
- Synonyms
- CARDIF antibody, IPS-1 antibody, IPS1 antibody, VISA antibody, D430028G21Rik antibody, Visa antibody, cardif antibody, wu:fj20d04 antibody, zgc:158392 antibody, mitochondrial antiviral signaling protein antibody, MAVS antibody, Mavs antibody, mavs antibody
- Background
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Description: Required for innate immune defense against viruses. Acts downstream of DHX33, DDX58/RIG-I and IFIH1/MDA5, which detect intracellular dsRNA produced during viral replication, to coordinate pathways leading to the activation of NF-kappa-B, IRF3 and IRF7, and to the subsequent induction of antiviral cytokines such as IFN-beta and RANTES (CCL5). Peroxisomal and mitochondrial MAVS act sequentially to create an antiviral cellular state. Upon viral infection, peroxisomal MAVS induces the rapid interferon-independent expression of defense factors that provide short-term protection, whereas mitochondrial MAVS activates an interferon-dependent signaling pathway with delayed kinetics, which amplifies and stabilizes the antiviral response. May activate the same pathways following detection of extracellular dsRNA by TLR3. May protect cells from apoptosis.
Gene: MAVS
- Molecular Weight
- 70-75 kDa
- Gene ID
- 57506
- UniProt
- Q7Z434
- Pathways
- Activation of Innate immune Response, Inositol Metabolic Process, Hepatitis C
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