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DKK1 antibody (AA 1-266)

DKK1 Reactivity: Human, Rat, Mouse WB, IHC (p), IF Host: Rabbit Polyclonal RB52126 unconjugated
Catalog No. ABIN6242718
  • Target See all DKK1 Antibodies
    DKK1 (Dickkopf Homolog 1 (DKK1))
    Binding Specificity
    • 15
    • 11
    • 11
    • 8
    • 7
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-266
    Reactivity
    • 121
    • 32
    • 28
    • 18
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Mouse
    Host
    • 116
    • 12
    • 1
    • 1
    Rabbit
    Clonality
    • 108
    • 22
    Polyclonal
    Conjugate
    • 60
    • 13
    • 10
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DKK1 antibody is un-conjugated
    Application
    • 87
    • 49
    • 21
    • 17
    • 14
    • 13
    • 7
    • 5
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This DKK1 antibody is generated from a rabbit immunized with a recombinant protein of human DKK1.
    Clone
    RB52126
    Isotype
    Ig Fraction
  • Application Notes
    IF: 1:25. WB: 1:1000. WB: 1:2000. WB: 1:4000. WB: 1:2000. IHC-P-Leica: 1:500. IHC-P-Leica: 1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Target
    DKK1 (Dickkopf Homolog 1 (DKK1))
    Alternative Name
    DKK1 (DKK1 Products)
    Synonyms
    DKK-1 antibody, SK antibody, AI414495 antibody, SGY antibody, SGY-1 antibody, SGY1 antibody, Soggy antibody, mSgy antibody, dkk1 antibody, dkk antibody, dkk-1 antibody, xdkk1 antibody, Xdkk-1 antibody, Dickkopf1 antibody, dickkopf-1 antibody, mdkk-1 antibody, dkk1-A antibody, dickkopf WNT signaling pathway inhibitor 1 antibody, dickkopf like acrosomal protein 1 antibody, dickkopf-related protein 1 antibody, dickkopf-like 1 antibody, dickkopf WNT signaling pathway inhibitor 1b antibody, dickkopf protein antibody, dickkopf WNT signaling pathway inhibitor 1 S homeolog antibody, DKK1 antibody, Dkk1 antibody, DKKL1 antibody, LOC100228789 antibody, Dkkl1 antibody, dkk1b antibody, dkk1 antibody, dickkopf antibody, dkk1.S antibody
    Background
    Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero- posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
    Molecular Weight
    28672
    UniProt
    O94907
    Pathways
    WNT Signaling, Regulation of Muscle Cell Differentiation, Positive Regulation of fat Cell Differentiation
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