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DKK1 Products

(Dickkopf Homolog 1 (DKK1))

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This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma. [provided by RefSeq, Jul 2008].

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Featured DKK1 Categories

DKK1 Antibodies

High quality antibodies with extensive validation data.

DKK1 ELISA Kits

Reliable ELISA kits for a wide range of species.

DKK1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended DKK1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p), IF
Validations
  • (7)
Cat. No. ABIN6242718
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IP, IHC (p)
Validations
  • (6)
  • (5)
Cat. No. ABIN524880
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7426013
Quantity 100 μL
Datasheet Datasheet

Recommended DKK1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966355
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955382
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955384
Quantity 96 tests
Datasheet Datasheet

Recommended DKK1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7274469
Quantity 100 μg
Datasheet Datasheet
Reactivity Cynomolgus, Rhesus Monkey
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274467
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274472
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our DKK1 products

Kared, Tan, Lau, Chevrier, Tan, How, Wong, Strickland, Malleret, Amoah, Pilipow, Zanon, Govern, Lum, Chen, Lee, Florian, Geiger, Ginhoux, Ruiz-Mateos, Fulop, Rajasuriar, Kamarulzaman, Ng, Lugli, Larbi: "Immunological history governs human stem cell memory CD4 heterogeneity via the Wnt signaling pathway." in: Nature communications, Vol. 11, Issue 1, pp. 821, (2020) (PubMed).

Wang, Xue, Wu, Ma, Wang, Li: "Role of sclerostin and dkk1 in bone remodeling in type 2 diabetic patients." in: Endocrine research, Vol. 43, Issue 1, pp. 29-38, (2018) (PubMed).

Xu, Ong, Zhu, Liu, Liu, Zhou, Xu, Gao, Zhang, Ye, Yang: "In Situ Release of VEGF Enhances Osteogenesis in 3D Porous Scaffolds Engineered with Osterix-Modified Adipose-Derived Stem Cells." in: Tissue engineering. Part A, Vol. 23, Issue 9-10, pp. 445-457, (2018) (PubMed).

Niessner, Kosnopfel, Sinnberg, Beck, Krieg, Wanke, Lasithiotakis, Bonin, Garbe, Meier: "Combined activity of temozolomide and the mTOR inhibitor temsirolimus in metastatic melanoma involves DKK1." in: Experimental dermatology, Vol. 26, Issue 7, pp. 598-606, (2018) (PubMed).

Wu, Liu, Meng, Qu, Fu, Wang, Yang, Jin, Yu: "Neuropeptide Y enhances proliferation and prevents apoptosis in rat bone marrow stromal cells in association with activation of the Wnt/β-catenin pathway in vitro." in: Stem cell research, Vol. 21, pp. 74-84, (2018) (PubMed).

Pontremoli, Brioschi, Baetta, Ghilardi, Banfi: "Identification of DKK-1 as a novel mediator of statin effects in human endothelial cells." in: Scientific reports, Vol. 8, Issue 1, pp. 16671, (2018) (PubMed).

Duan, Yan, Chen, Wu, Han, Guo, Qiao: "TET1 inhibits EMT of ovarian cancer cells through activating Wnt/β-catenin signaling inhibitors DKK1 and SFRP2." in: Gynecologic oncology, Vol. 147, Issue 2, pp. 408-417, (2017) (PubMed).

Li, Chen, Zhang, Ren, Chen, Cao, Zang, Liu, Guo: "Small Interfering RNA Targeting Dickkopf-1 Contributes to Neuroprotection After Intracerebral Hemorrhage in Rats." in: Journal of molecular neuroscience : MN, Vol. 61, Issue 2, pp. 279-288, (2017) (PubMed).

Lu, Duan, Zhang, Wu, Wang: "Expression of Wnt3a, Wnt10b, ?-catenin and DKK1 in periodontium during orthodontic tooth movement in rats." in: Acta odontologica Scandinavica, pp. 1-7, (2015) (PubMed).

Sugatani, Agapova, Malluche, Hruska: "SIRT6 deficiency culminates in low-turnover osteopenia." in: Bone, Vol. 81, pp. 168-77, (2015) (PubMed).

Synonyms and alternative names related to DKK1

dickkopf WNT signaling pathway inhibitor 1 (DKK1), dickkopf WNT signaling pathway inhibitor 1 (Dkk1), dickkopf like acrosomal protein 1 (DKKL1), dickkopf-related protein 1 (LOC100228789), dickkopf-like 1 (Dkkl1), dickkopf WNT signaling pathway inhibitor 1b (dkk1b), dickkopf WNT signaling pathway inhibitor 1 (dkk1), dickkopf protein (dickkopf), dickkopf WNT signaling pathway inhibitor 1 S homeolog (dkk1.S), AI414495, dickkopf-1, Dickkopf1, dkk, DKK-1, dkk-1, dkk1, dkk1-A, mdkk-1, mSgy, SGY, SGY-1, SGY1, SK, Soggy, Xdkk-1, xdkk1

Protein level used designations for DKK1

  • dickkopf 1 homolog
  • dickkopf related protein-1
  • dickkopf-1 like
  • dickkopf-like protein 1
  • dickkopf-related protein 1
  • hDkk-1
  • dickkopf homolog 1
  • dickkopf-like 1
  • dickkopf-like 1 (soggy)
  • dickkopf1
  • protein soggy-1
  • soggy 1
  • dickkopf 1
  • dickkopf protein
  • Ci-dickkopf
  • dickkopf-1
  • dkk-1
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