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PLEKHA8 antibody
PLEKHA8
Reactivity: Human, Mouse, Rat
ELISA, WB, IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-PLEKHA8 Antibody
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Target
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PLEKHA8
(Pleckstrin Homology Domain Containing, Family A (Phosphoinositide Binding Specific) Member 8 (PLEKHA8))
Reactivity
Human, Mouse, Rat
Host
All hosts for PLEKHA8 antibodies
Rabbit
Clonality
All clonalities for PLEKHA8 antibodies
Polyclonal
Conjugate
All conjugates for PLEKHA8 antibodies
This PLEKHA8 antibody is un-conjugated
Application
All applications for PLEKHA8 antibodies
ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
Purification
Immunogen affinity purified
Purity
≥95 % as determined by SDS-PAGE
Immunogen
pleckstrin homology domain containing, family A(phosphoinositide binding specific) member 8
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
WB: 1:500-1:2000, IHC: 1:20-1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Expiry Date
12 months
Target Details for PLEKHA8
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Target
PLEKHA8
(Pleckstrin Homology Domain Containing, Family A (Phosphoinositide Binding Specific) Member 8 (PLEKHA8))
Alternative Name
PLEKHA8 (PLEKHA8 Products )
Synonyms
FAPP-2 antibody, RGD1563940 antibody, FAPP2 antibody, 6330400G01 antibody, AA517676 antibody, BC052360 antibody, Fapp-2 antibody, Fapp2 antibody, pleckstrin homology domain containing A8 antibody, pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8 antibody, Plekha8 antibody, PLEKHA8 antibody, plekha8 antibody
Background
Synonyms:FAPP2 Background:Cargo transport protein that is required for apical transport from the Golgi complex. Transports AQP2 from the trans-Golgi network(TGN) to sites of AQP2 phosphorylation. Mediates the non-vesicular transport of glucosylceramide(GlcCer) from the trans-Golgi network(TGN) to the plasma membrane and plays a pivotal role in the synthesis of complex glycosphingolipids. Binding of both phosphatidylinositol 4-phosphate(PIP) and ARF1 are essential for the GlcCer transfer ability. Also required for primary cilium formation, possibly by being involved in the transport of raft lipids to the apical membrane, and for membrane tubulation.
Molecular Weight
49 kDa
Gene ID
84725
UniProt
Q96JA3
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