ARIH1 antibody
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- Target See all ARIH1 Antibodies
- ARIH1 (Ariadne Homolog, Ubiquitin-Conjugating Enzyme E2 Binding Protein, 1 (ARIH1))
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ARIH1 antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC)
- Characteristics
- Polyclonal Antibody
- Purification
- Antigen affinity purification
- Immunogen
- Synthetic peptide of human ARIH1
- Isotype
- IgG
- Top Product
- Discover our top product ARIH1 Primary Antibody
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anti-Ariadne Homolog, Ubiquitin-Conjugating Enzyme E2 Binding Protein, 1 (ARIH1) (C-Term) antibody
Verified ARIH1 Reactivity: Human WB, ELISA, IHC Host: Goat Polyclonal unconjugated
anti-Ariadne Homolog, Ubiquitin-Conjugating Enzyme E2 Binding Protein, 1 (ARIH1) (C-Term) antibodyARIH1 Reactivity: Human, Mouse, Cow, Dog, Zebrafish (Danio rerio), Guinea Pig, Horse, Rabbit, Rat, Monkey, Bat, Pig, Chicken WB Host: Rabbit Polyclonal unconjugated
anti-Ariadne Homolog, Ubiquitin-Conjugating Enzyme E2 Binding Protein, 1 (ARIH1) (C-Term) antibodyARIH1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Ariadne Homolog, Ubiquitin-Conjugating Enzyme E2 Binding Protein, 1 (ARIH1) (C-Term) antibodyARIH1 Reactivity: Human, Mouse, Cow, Dog, Zebrafish (Danio rerio), Guinea Pig, Horse, Rabbit, Rat WB Host: Rabbit Polyclonal unconjugated
anti-Ariadne Homolog, Ubiquitin-Conjugating Enzyme E2 Binding Protein, 1 (ARIH1) antibodyARIH1 Reactivity: Human, Mouse, Dog, Zebrafish (Danio rerio) WB, ELISA Host: Rabbit Polyclonal unconjugated
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- Application Notes
- IHC 1:50-1:100, ELISA 1:5000-1:10000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.9 mg/mL
- Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- ARIH1 (Ariadne Homolog, Ubiquitin-Conjugating Enzyme E2 Binding Protein, 1 (ARIH1))
- Alternative Name
- ARIH1 (ARIH1 Products)
- Synonyms
- ARIH1 antibody, ARI-1 antibody, ari antibody, ariadne antibody, hari antibody, hhari antibody, ubch7bp antibody, ARI antibody, HARI antibody, HHARI antibody, UBCH7BP antibody, AU021774 antibody, Ari antibody, Ari1 antibody, Hari antibody, Hhari antibody, Ubch7bp antibody, Uip77 antibody, wu:fa18d01 antibody, zgc:66364 antibody, ariadne RBR E3 ubiquitin protein ligase 1 antibody, ariadne RBR E3 ubiquitin protein ligase 1 L homeolog antibody, ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila) antibody, Arih1 antibody, ARIH1 antibody, arih1 antibody, arih1.L antibody
- Background
- ARIH1 (ariadne homolog), also known as ubiquitin conjugating enzyme E2 binding protein 1, ARI, HARI, HHARI (human homolog of Drosophila ariadne), MOP-6 (monocyte protein 6) or UBCH7BP (UBCH7 binding protein), is a 557 amino acid cytoplasmic protein. Expressed in a wide variety of tissues, ARIH1 contains two RING-type zinc fingers and one IBR (in-between RING fingers)-type domain. ARIH1 is believed to be involved in protein degradation and protein translation. ARIH1 interacts with UBCH7 and is thought to function as an E3 ubiquitin-protein ligase (or as a component of an E3 complex) that, characteristic of E3 ligase proteins, accepts ubiquitin (in the form of a thioester) from an E2 ubiquitin-conjugating enzyme (UBCH7) and transfers that ubiquitin residue to substrates targeted for degradation. Specifically, ARIH1 interacts with and polyubiquitylates eIF4E2, thereby targeting it for proteasomal degradation.
- UniProt
- Q9Y4X5
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