GLUT4 antibody (AA 333-509)
(4 references)-
- Target See all GLUT4 (SLC2A4) Antibodies
- GLUT4 (SLC2A4) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4))
-
Binding Specificity
- AA 333-509
-
Reactivity
- Human, Mouse, Rat
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This GLUT4 antibody is un-conjugated
-
Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Purpose
- Rabbit IgG polyclonal antibody for Solute carrier family 2, facilitated glucose transporter member 4(SLC2A4) detection. Tested with WB, IHC-P, IHC-F in Human,Mouse,Rat.
- Cross-Reactivity (Details)
- No cross reactivity with other proteins.
- Characteristics
-
Rabbit IgG polyclonal antibody for Solute carrier family 2, facilitated glucose transporter member 4(SLC2A4) detection. Tested with WB, IHC-P, IHC-F in Human,Mouse,Rat.
Gene Name: solute carrier family 2 (facilitated glucose transporter), member 4
Protein Name: Solute carrier family 2, facilitated glucose transporter member 4 - Purification
- Immunogen affinity purified.
- Immunogen
- E.coli-derived human GLUT4 recombinant protein (Position: N333-D509). Human GLUT4 shares 97% amino acid (aa) sequence identity with mouse GLUT4.
- Isotype
- IgG
- Top Product
- Discover our top product SLC2A4 Primary Antibody
-
anti-Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4) (AA 224-353) antibody
SLC2A4 Reactivity: Human, Mouse WB, IHC, ELISA, ICC, FACS Host: Mouse Monoclonal 3G10A3 unconjugated
anti-Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4) (C-Term) antibodySLC2A4 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4) (AA 401-509) antibodySLC2A4 Reactivity: Human, Mouse, Rat, Pig, Goat, Sheep WB, ELISA, IHC (p), IHC (fro), FACS, IF (cc), IF (p) Host: Rabbit Polyclonal unconjugated
anti-Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4) (AA 224-353) antibodySLC2A4 Reactivity: Human, Mouse WB, IHC, ELISA, IF/ICC, FACS Host: Mouse Monoclonal unconjugated
anti-Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4) (AA 223-287) antibodySLC2A4 Reactivity: Human WB, IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4) (N-Term) antibodySLC2A4 Reactivity: Human, Mouse, Rat, Rabbit, Cow, Goat, Horse, Dog, Guinea Pig, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
anti-Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4) (N-Term) antibodySLC2A4 Reactivity: Human, Mouse, Rat WB, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4) antibodySLC2A4 Reactivity: Human, Mouse, Rat WB, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4) antibodySLC2A4 Reactivity: Human, Mouse, Rat IHC Host: Rabbit Polyclonal unconjugated
anti-Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4) (AA 228-292) antibodySLC2A4 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
-
- Application Notes
-
WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat, Predicted Species: Human, The detection limit for GLUT4 is approximately 0.25 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
IHC-F: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Rat
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. - Comment
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and IHC(F).
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
-
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
-
-
: "Inhibition of insulin resistance by PGE1 via autophagy-dependent FGF21 pathway in diabetic nephropathy." in: Scientific reports, Vol. 8, Issue 1, pp. 9, (2018) (PubMed).
: "lncRNA Ftx promotes aerobic glycolysis and tumor progression through the PPARγ pathway in hepatocellular carcinoma." in: International journal of oncology, Vol. 53, Issue 2, pp. 551-566, (2018) (PubMed).
: "Acupuncture Alters Expression of Insulin Signaling Related Molecules and Improves Insulin Resistance in OLETF Rats." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2016, pp. 9651592, (2016) (PubMed).
: "AMP-activated protein kinase is required for the anti-adipogenic effects of alpha-linolenic acid." in: Nutrition & metabolism, Vol. 12, pp. 10, (2015) (PubMed).
-
: "Inhibition of insulin resistance by PGE1 via autophagy-dependent FGF21 pathway in diabetic nephropathy." in: Scientific reports, Vol. 8, Issue 1, pp. 9, (2018) (PubMed).
-
- Target
- GLUT4 (SLC2A4) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4))
- Alternative Name
- SLC2A4 (SLC2A4 Products)
- Synonyms
- GLUT4 antibody, Glut-4 antibody, Glut4 antibody, glut4 antibody, slc2a4 antibody, SLC2A4 antibody, solute carrier family 2 member 4 antibody, solute carrier family 2 (facilitated glucose transporter), member 4 antibody, solute carrier family 2 (facilitated glucose transporter), member 4 L homeolog antibody, SLC2A4 antibody, Slc2a4 antibody, GLUT4 antibody, slc2a4.L antibody
- Background
-
GLUT4, also known as SLC2A4 or solute carrier family 2 (facilitated glucose transporter) member 4, is a protein that in humans is encoded by the GLUT4 gene. It is mapped to 17p13.1. This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM).
Synonyms: insulin-responsive antibody|Glucose transporter GLUT 4 antibody|Glucose transporter type 4 antibody|Glucose transporter type 4 insulin responsive antibody|GLUT 4 antibody|GLUT-4 antibody|GLUT4 antibody|GTR4_HUMAN antibody|kug antibody|SLC 2A4 antibody|SLC2A4 antibody|solute carrier family 2 (facilitated glucose transporter) member 4 antibody|Solute carrier family 2, facilitated glucose transporter member 4 antibody - Gene ID
- 6517
- UniProt
- P14672
- Pathways
- AMPK Signaling, Carbohydrate Homeostasis, Proton Transport, Brown Fat Cell Differentiation, Warburg Effect
-
