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HMOX1 antibody

Name: HMOX1 antibody
Brand: antibodies-online
SKU: ABIN2854952
Price: 609.18 USD
Availability: InStock

KO Validated HMOX1 Reactivity: Human WB, ELISA, ICC, IF, IHC (p) Host: Rabbit Polyclonal unconjugated

WB Image Untreated (–) and treated (+) HeLa whole cell extracts (30 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with Heme Oxygenase 1 antibody , diluted at 1:1000.

IHC-P Image Heme Oxygenase 1 antibody detects HMOX1 protein at cytoplasm in rat spleen by immunohistochemical analysis.

IHC

WB Image Heme Oxygenase 1 antibody detects Heme Oxygenase 1 protein by western blot analysis.

WB Image Various whole cell extracts (30 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with Heme Oxygenase 1 antibody , diluted at 1:1500.

IHC-P Image Heme Oxygenase 1 antibody detects Heme Oxygenase 1 protein at cytoplasm on human renal carcinoma by immunohistochemical analysis.

IHC

ICC/IF Image Heme Oxygenase 1 antibody detects Heme Oxygenase 1 protein at nucleus and cytoplasm by immunofluorescent analysis.

8 images

(6 references)

Catalog No. ABIN2854952

Datasheet as PDF

Target See all HMOX1 Antibodies

HMOX1 (Heme Oxygenase (Decycling) 1 (HMOX1))
Reactivity
115

62

44

15

11

9

9

8

7

5

2

2

2

2

2
Human
Host
121

45

2

1

1
Rabbit
Compatible Secondaries
Clonality
117

53
Polyclonal
Conjugate
77

20

16

9

8

8

6

4

4

4

2

2

2

2

2

2

2
This HMOX1 antibody is un-conjugated
Application
142

77

55

51

48

39

23

10

5

3

3

3

2

1

1
Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity

Human, Monkey, Mouse, Rat

Characteristics

Rabbit Polyclonal antibody to Heme Oxygenase 1 (heme oxygenase (decycling) 1)
Heme Oxygenase 1 antibody

Purification

Purified by antigen-affinity chromatography.

Grade

KO Validated

Immunogen

Recombinant protein encompassing a sequence within the center region of human Heme Oxygenase 1. The exact sequence is proprietary.

Isotype

IgG
anti-Heme Oxygenase (Decycling) 1 (HMOX1) (AA 1-30) antibody
HMOX1 Reactivity: Human WB, IHC, IP, ELISA, ICC, IF Host: Mouse Monoclonal 1F12-A6 unconjugated

anti-Heme Oxygenase (Decycling) 1 (HMOX1) (AA 1-30) antibody (HRP)
HMOX1 Reactivity: Human WB, IHC, IP, ELISA, ICC, IF Host: Mouse Monoclonal 1F12-A6 HRP

anti-Heme Oxygenase (Decycling) 1 (HMOX1) (AA 1-288) antibody
HMOX1 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-Heme Oxygenase (Decycling) 1 (HMOX1) antibody
HMOX1 Reactivity: Human WB, IHC Host: Rabbit Monoclonal unconjugated

anti-Heme Oxygenase (Decycling) 1 (HMOX1) (N-Term) antibody
HMOX1 Reactivity: Human, Rat, Mouse, Pig, Dog, Cow, Rabbit, Guinea Pig, Goat WB Host: Rabbit Polyclonal unconjugated

anti-Heme Oxygenase (Decycling) 1 (HMOX1) (AA 99-237) antibody
HMOX1 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Heme Oxygenase (Decycling) 1 (HMOX1) (AA 61-172) antibody
HMOX1 Reactivity: Human WB, IHC, IP, ICC Host: Mouse Monoclonal A4 unconjugated

anti-Heme Oxygenase (Decycling) 1 (HMOX1) (AA 61-172) antibody
HMOX1 Reactivity: Pig WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Heme Oxygenase (Decycling) 1 (HMOX1) (AA 1-30) antibody (FITC)
HMOX1 Reactivity: Human WB, IHC, IP, ELISA, ICC, IF Host: Mouse Monoclonal 1F12-A6 FITC

anti-Heme Oxygenase (Decycling) 1 (HMOX1) (AA 1-30) antibody (Biotin)
HMOX1 Reactivity: Human WB, IHC, IP, ELISA, ICC, IF Host: Mouse Monoclonal 1F12-A6 Biotin

Application Notes

WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment

Positive Control: Raw264.7 , C2C12
Validation: KO/KD, Orthogonal

Restrictions

For Research Use only
Format

Liquid

Concentration

0.45 mg/mL

Buffer

1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

Preservative

ProClin

Precaution of Use

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C,-20 °C

Storage Comment

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Batubara, Astuti, Prastya, Ilmiawati, Maeda, Suzuki, Hamamoto, Takemori: "The Antiaging Effect of Active Fractions and Ent-11α-Hydroxy-15-Oxo-Kaur-16-En-19-Oic Acid Isolated from Adenostemma lavenia (L.) O. Kuntze at the Cellular Level." in: Antioxidants (Basel, Switzerland), Vol. 9, Issue 8, (2020) (PubMed).

Neitzel, Seiwert, Göder, Diehl, Weber, Nagel, Stroh, Rasenberger, Christmann, Fahrer: "Lipoic Acid Synergizes with Antineoplastic Drugs in Colorectal Cancer by Targeting p53 for Proteasomal Degradation." in: Cells, Vol. 8, Issue 8, (2020) (PubMed).

Tsai, Jou, Tsai, Shiau, Wu, Tzai et al.: "Prothymosin-α enhances phosphatase and tensin homolog expression and binds with tripartite motif-containing protein 21 to regulate Kelch-like ECH-associated protein 1/nuclear factor erythroid ..." in: Cancer science, Vol. 110, Issue 4, pp. 1208-1219, (2019) (PubMed).

Yeh, Wu, Cheng, Tsai, Chang, Yeh, Wu, Lee, Chiang: "HO-1 is a favorable prognostic factor for HBV-HCC patients who underwent hepatectomy." in: Cancer management and research, Vol. 10, pp. 6049-6059, (2018) (PubMed).

Ugun-Klusek, Tatham, Elkharaz, Constantin-Teodosiu, Lawler, Mohamed, Paine, Anderson, John Mayer, Lowe, Ellen Billett, Bedford: "Continued 26S proteasome dysfunction in mouse brain cortical neurons impairs autophagy and the Keap1-Nrf2 oxidative defence pathway." in: Cell death & disease, Vol. 8, Issue 1, pp. e2531, (2017) (PubMed).

Xu, Wu, Zheng, Yu, Yang, Yao, Zhou, Ching, Lau: "Proteome profiling of cadmium-induced apoptosis by antibody array analyses in human bronchial epithelial cells." in: Oncotarget, Vol. 7, Issue 5, pp. 6146-58, (2017) (PubMed).
Target

HMOX1 (Heme Oxygenase (Decycling) 1 (HMOX1))

Alternative Name

heme oxygenase 1 (HMOX1 Products)

Synonyms

HMOX1 antibody, ARABIDOPSIS THALIANA HEME OXYGENASE 1 antibody, ATHO1 antibody, F18A8.4 antibody, F18A8_4 antibody, GENOMES UNCOUPLED 2 antibody, GUN2 antibody, HEME OXYGENASE antibody, HEME OXYGENASE 1 antibody, HEME OXYGENASE 6 antibody, HO1 antibody, HY1 antibody, HY6 antibody, PLASTID HEME OXYGENASE antibody, REVERSAL OF THE DET PHENOTYPE 4 antibody, HO-1 antibody, wu:fc27c04 antibody, zgc:65984 antibody, D8Wsu38e antibody, Hemox antibody, Hmox antibody, Hsp32 antibody, HEOXG antibody, Heox antibody, Ho-1 antibody, Ho1 antibody, hsp32 antibody, MGC132176 antibody, Hmox1 antibody, HMOX1D antibody, HSP32 antibody, bK286B10 antibody, heme oxygenase 1 antibody, Plant heme oxygenase (decyclizing) family protein antibody, Heme oxygenase antibody, heme oxygenase antibody, heme oxygenase 1, chloroplastic antibody, heme oxygenase 1a antibody, heme oxygenase 1 L homeolog antibody, HMOX1 antibody, TED4 antibody, ho1 antibody, P9301_RS17555 antibody, A9601_RS17590 antibody, MAE_RS06565 antibody, HO1 antibody, hmox1a antibody, CPE0214 antibody, Cyan7425_2962 antibody, Hmox1 antibody, hmox1.L antibody, AM1_C0205 antibody, CC1G_11686 antibody, CpipJ_CPIJ007246 antibody

Background

Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family.

Cellular Localization: Microsome , Endoplasmic reticulum

Molecular Weight

33 kDa

Gene ID

3162

UniProt

P09601

Pathways

Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, SARS-CoV-2 Protein Interactome