Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

MSL1 antibody (AA 210-300)

MSL1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7268383
  • Target See all MSL1 Antibodies
    MSL1 (Male-Specific Lethal 1 Homolog (MSL1))
    Binding Specificity
    • 8
    • 7
    • 6
    • 6
    • 1
    • 1
    AA 210-300
    Reactivity
    • 18
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 18
    Rabbit
    Clonality
    • 18
    Polyclonal
    Conjugate
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
    This MSL1 antibody is un-conjugated
    Application
    • 17
    • 14
    Western Blotting (WB)
    Purpose
    MSL1 Rabbit pAb
    Sequence
    LAVPSWRDHS VEPLRDPNPS DLLENLDDSV FSKRHAKLEL DEKRRKRWDI QRIREQRILQ RLQLRMYKKK GIQESEPEVT SFFPEPDDVE S
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 210-300 of human MSL1 (NP_001012241).
    Isotype
    IgG
  • Application Notes
    WB,1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    MSL1 (Male-Specific Lethal 1 Homolog (MSL1))
    Alternative Name
    MSL1 (MSL1 Products)
    Synonyms
    MSL-1 antibody, hMSL1 antibody, 2810017F12Rik antibody, 4121402D02Rik antibody, 4930463F05Rik antibody, AA682082 antibody, Msl-1 antibody, male specific lethal 1 homolog antibody, male-specific lethal 1 homolog (Drosophila) antibody, MSL1 antibody, Msl1 antibody
    Background
    Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at 'Lys-16' (H4K16ac which is implicated in the formation of higher-order chromatin structure. Greatly enhances MSL2 E3 ubiquitin ligase activity, promoting monoubiquitination of histone H2B at 'Lys-34' (H2BK34Ub. This modification in turn stimulates histone H3 methylation at 'Lys-4' (H3K4me and 'Lys-79' (H3K79me and leads to gene activation, including that of HOXA9 and MEIS1. In the MSL complex, acts as a scaffold to tether MSL3 and KAT8 together for enzymatic activity regulation.,MSL-1,hMSL1,MSL1,Epigenetics & Nuclear Signaling,Histones,MSL1
    Gene ID
    339287
    UniProt
    Q68DK7
You are here:
Support