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HDAC5 antibody

HDAC5 Reactivity: Human, Mouse, Rat, Cow, Dog, Pig WB, IHC (p), IF (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN681043
  • Target See all HDAC5 Antibodies
    HDAC5 (Histone Deacetylase 5 (HDAC5))
    Reactivity
    • 78
    • 57
    • 42
    • 32
    • 27
    • 17
    • 12
    • 2
    • 2
    • 2
    • 1
    Human, Mouse, Rat, Cow, Dog, Pig
    Host
    • 76
    • 2
    Rabbit
    Clonality
    • 76
    • 2
    Polyclonal
    Conjugate
    • 48
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This HDAC5 antibody is un-conjugated
    Application
    • 69
    • 25
    • 24
    • 22
    • 21
    • 17
    • 7
    • 5
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Cow, Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human HDAC5
    Isotype
    IgG
    Top Product
    Discover our top product HDAC5 Primary Antibody
  • Application Notes
    WB(1:100-500)
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for 12 months.
    Expiry Date
    12 months
  • Target
    HDAC5 (Histone Deacetylase 5 (HDAC5))
    Alternative Name
    HDAC5 (HDAC5 Products)
    Synonyms
    HD5 antibody, NY-CO-9 antibody, AI426555 antibody, Hdac4 antibody, mHDA1 antibody, mKIAA0600 antibody, ATHDA5 antibody, HDA5 antibody, MAF19.7 antibody, MAF19_7 antibody, histone deacetylase 5 antibody, histone deacetylase 5 antibody, HDAC5 antibody, Hdac5 antibody, HDA05 antibody, hdac5 antibody
    Background

    Synonyms: HDAC4: Histone deacetylase 4, HD4 HDAC 5, Histone deacetylase 5, HD5, Antigen NY-CO-9

    Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]..

    Molecular Weight
    122kDa
    Gene ID
    9759, 10014
    UniProt
    P56524, Q9UQL6
    Pathways
    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Monocarboxylic Acid Catabolic Process
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