NPLOC4 antibody (AA 1-270)
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- Target See all NPLOC4 Antibodies
- NPLOC4 (Nuclear Protein Localization 4 Homolog (NPLOC4))
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Binding Specificity
- AA 1-270
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NPLOC4 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Sequence
- MAESIIIRVQ SPDGVKRITA TKRETAATFL KKVAKEFGFQ NNGFSVYINR NKTGEITASS NKSLNLLKIK HGDLLFLFPS SLAGPSSEME TSVPPGFKVF GAPNVVEDEI DQYLSKQDGK IYRSRDPQLC RHGPLGKCVH CVPLEPFDED YLNHLEPPVK HMSFHAYIRK LTGGADKGKF VALENISCKI KSGCEGHLPW PNGICTKCQP SAITLNRQKY RHVDNIMFEN HTVADRFLDF WRKTGNQHFG YLYGRYTEHK DIPLGIRAEV
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human NPLOC4 (NP_060391.2).
- Isotype
- IgG
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anti-Nuclear Protein Localization 4 Homolog (NPLOC4) (AA 1-608) antibody
NPLOC4 Reactivity: Human WB, IP, IF Host: Rabbit Polyclonal unconjugated
anti-Nuclear Protein Localization 4 Homolog (NPLOC4) (AA 1-608) antibodyNPLOC4 Reactivity: Human WB, IF Host: Mouse Polyclonal unconjugated
anti-Nuclear Protein Localization 4 Homolog (NPLOC4) (AA 456-484), (C-Term) antibodyNPLOC4 Reactivity: Human WB Host: Rabbit Polyclonal RB37356 unconjugated
anti-Nuclear Protein Localization 4 Homolog (NPLOC4) (AA 96-145) antibodyNPLOC4 Reactivity: Human, Mouse WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB,1:1000 - 1:2000,IF,1:50 - 1:200
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- NPLOC4 (Nuclear Protein Localization 4 Homolog (NPLOC4))
- Alternative Name
- NPLOC4 (NPLOC4 Products)
- Synonyms
- NPL4 antibody, AK129375 antibody, Npl4 antibody, mKIAA1499 antibody, NPL4 homolog, ubiquitin recognition factor antibody, NPLOC4 antibody, Nploc4 antibody
- Background
- The ternary complex containing UFD1, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope (By similarity. Acts as a negative regulator of type I interferon production via the complex formed with VCP and UFD1, which binds to DDX58/RIG-I and recruits RNF125 to promote ubiquitination and degradation of DDX58/RIG-I.,NPLOC4,NPL4,NPL4 homolog,Signal Transduction,NPLOC4
- Molecular Weight
- 68 kDa/69 kDa
- Gene ID
- 55666
- UniProt
- Q8TAT6
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