NPLOC4 antibody (AA 525-575)

Catalog No. ABIN7451285

Product Details anti-NPLOC4 Antibody

Target: NPLOC4 (Nuclear Protein Localization 4 Homolog (NPLOC4))

Binding Specificity: AA 525-575

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPLOC4 antibody is un-conjugated

Application: Immunoprecipitation (IP)

Purpose: Rabbit anti-NPL4 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 525 and 575

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: Not recommended. Use rabbit anti-NPL4 antibody A304-102A.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for NPLOC4

Target: NPLOC4 (Nuclear Protein Localization 4 Homolog (NPLOC4))

Alternative Name: NPL4 (NPLOC4 Products)

Synonyms: NPL4 antibody, AK129375 antibody, Npl4 antibody, mKIAA1499 antibody, NPL4 homolog, ubiquitin recognition factor antibody, NPLOC4 antibody, Nploc4 antibody

Background: Background: Nuclear protein localization protein 4 homolog (NPL4) is part of a ternary complex containing UFD1L, VCP and NPL4. The complex binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPL4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope (by similarity)[taken from the Universal Protein Resource (UniProt) Q8TAT6].

Gene ID: 55666

NCBI Accession: NP_060391

UniProt: Q8TAT6