RAD51 Homolog B antibody
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- Target See all RAD51 Homolog B (Rad51B) Antibodies
- RAD51 Homolog B (Rad51B)
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Reactivity
- Human, Mouse, Monkey
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This RAD51 Homolog B antibody is un-conjugated
- Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- RAD51L1 Antibody detects endogenous levels of total RAD51L1
- Cross-Reactivity
- Human, Monkey, Mouse (Murine)
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide
- Isotype
- IgG
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anti-RAD51 Homolog B (Rad51B) (Middle Region) antibody
Rad51B Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Horse WB Host: Rabbit Polyclonal unconjugated
anti-RAD51 Homolog B (Rad51B) (AA 1-384) antibodyRad51B Reactivity: Human WB, IF Host: Mouse Polyclonal unconjugated
anti-RAD51 Homolog B (Rad51B) (AA 251-300) antibodyRad51B Reactivity: Human, Mouse, Monkey, Cow WB Host: Rabbit Polyclonal unconjugated
anti-RAD51 Homolog B (Rad51B) (AA 143-192) antibodyRad51B Reactivity: Human, Monkey, Dog, Guinea Pig, Rabbit WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-RAD51 Homolog B (Rad51B) (Center) antibodyRad51B Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-RAD51 Homolog B (Rad51B) (AA 1-384) antibodyRad51B Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-RAD51 Homolog B (Rad51B) (AA 201-250) antibodyRad51B Reactivity: Human, Mouse WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:500~1:1000 IHC: 1:50~1:200, IF/ICC 1:100-1:500
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C.Stable for 12 months from date of receipt
- Expiry Date
- 12 months
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- Target
- RAD51 Homolog B (Rad51B)
- Alternative Name
- RAD51L1 (Rad51B Products)
- Synonyms
- R51H2 antibody, RAD51L1 antibody, REC2 antibody, AI553500 antibody, Rad51l1 antibody, mREC2 antibody, ATRAD51B antibody, T17D12.12 antibody, T17D12_12 antibody, RGD1560681 antibody, rad51l1 antibody, wu:fd07f04 antibody, zgc:56581 antibody, RAD51 paralog B antibody, DNA repair (Rad51) family protein antibody, Rad51 DNA recombinase 2 antibody, RAD51B antibody, Rad51b antibody, rad51b antibody
- Background
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Description: Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. May promote the assembly of presynaptic RAD51 nucleoprotein filaments. Binds single-stranded DNA and double-stranded DNA and has DNA-dependent ATPase activity. Part of the RAD21 paralog protein complex BCDX2 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, BCDX2 acts downstream of BRCA2 recruitment and upstream of RAD51 recruitment. BCDX2 binds predominantly to the intersection of the four duplex arms of the Holliday junction and to junction of replication forks. The BCDX2 complex was originally reported to bind single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA. The BCDX2 subcomplex RAD51B:RAD51C exhibits single-stranded DNA-dependent ATPase activity suggesting an involvement in early stages of the HR pathway.
Gene: RAD51B
- Molecular Weight
- 45 kDa
- Gene ID
- 5890
- UniProt
- O15315
- Pathways
- DNA Damage Repair
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