RNF5 antibody (AA 1-120)
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- Target See all RNF5 Antibodies
- RNF5 (Ring Finger Protein 5, E3 Ubiquitin Protein Ligase (RNF5))
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Binding Specificity
- AA 1-120
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This RNF5 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Cross-Reactivity
- Human, Mouse
- Purification
- Antigen Affinity Purified
- Immunogen
- Recombinant Human E3 ubiquitin-protein ligase RNF5 protein (1-120AA)
- Isotype
- IgG
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- Application Notes
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- RNF5 (Ring Finger Protein 5, E3 Ubiquitin Protein Ligase (RNF5))
- Alternative Name
- RNF5 (RNF5 Products)
- Synonyms
- 2410131O05Rik antibody, AA407576 antibody, NG2 antibody, RING5 antibody, RMA1 antibody, ring finger protein 5 antibody, Rnf5 antibody, RNF5 antibody
- Background
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Background: Has E2-dependent E3 ubiquitin-protein ligase activity. May function together with E2 ubiquitin-conjugating enzymes UBE2D1/UBCH5A and UBE2D2/UBC4. Mediates ubiquitination of PXN/paxillin and Salmonella type III secreted protein sopA. May be involved in regulation of cell motility and localization of PXN/paxillin. Mediates the \\\'Lys-63\\\'-linked polyubiquitination of JKAMP thereby regulating JKAMP function by decreasing its association with components of the proteasome and ERAD, the ubiquitination appears to involve E2 ubiquitin-conjugating enzyme UBE2N. Mediates the \\\'Lys-48\\\'-linked polyubiquitination of TMEM173 at \\\'Lys-150\\\' leading to its proteasomal degradation, the ubiquitination occurrs in mitochondria after viral transfection and regulates antiviral responses.
Aliases: E3 ubiquitin protein ligase RNF5 antibody, E3 ubiquitin-protein ligase RNF5 antibody, G16 antibody, HsRma1 antibody, NG2 antibody, OTTHUMP00000029107 antibody, Protein G16 antibody, Ram1 homolog antibody, RING finger protein 5 antibody, RING5 antibody, RMA1 antibody, RNF 5 antibody, RNF5 antibody, RNF5_HUMAN antibody
- UniProt
- Q99942
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