SCN4A antibody
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- Target See all SCN4A Antibodies
- SCN4A (Sodium Channel, Voltage-Gated, Type IV, alpha Subunit (SCN4A))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SCN4A antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Cross-Reactivity
- Human
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogen
- Synthesized peptide derived from internal of Human SCN4A.
- Isotype
- IgG
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- Application Notes
- WB:1:500-1:3000,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- SCN4A (Sodium Channel, Voltage-Gated, Type IV, alpha Subunit (SCN4A))
- Alternative Name
- SCN4A (SCN4A Products)
- Synonyms
- Nav1.4 antibody, SkM1 antibody, mH2 antibody, HOKPP2 antibody, HYKPP antibody, HYPP antibody, NAC1A antibody, Na(V)1.4 antibody, NCHVS antibody, microI antibody, Nav1.4b antibody, sodium channel, voltage-gated, type IV, alpha antibody, sodium voltage-gated channel alpha subunit 4 antibody, sodium channel, voltage-gated, type IV, alpha, b antibody, Scn4a antibody, SCN4A antibody, scn4ab antibody
- Background
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Background: This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient. This sodium channel may be present in both denervated and innervated skeletal muscle.
George A.L. Jr., Ann. Neurol. 31:131-137(1992).
Wang J., Biochem. Biophys. Res. Commun. 182:794-801(1992).
Tsujino A., Proc. Natl. Acad. Sci. U.S.A. 100:7377-7382(2003).Aliases: HYKPP antibody, HYPP antibody, Na(V)1.4 antibody, NAC1A antibody, Nav1.4 antibody, Scn4a antibody, SCN4A_HUMAN antibody, Skeletal muscle voltage dependent sodium channel type IV alpha subunit antibody, SkM1 antibody, Sodium channel protein skeletal muscle subunit alpha antibody, Sodium channel protein type 4 subunit alpha antibody, Sodium channel protein type IV subunit alpha antibody, Sodium channel voltage gated type IV alpha subunit antibody, Voltage gated sodium channel subunit alpha Nav1.4 antibody, Voltage gated sodium channel type 4 alpha antibody, Voltage-gated sodium channel subunit alpha Nav1.4 antibody
- UniProt
- P35499
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