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SMARCD1 antibody (AA 7-124)

SMARCD1 Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7171071
  • Target See all SMARCD1 Antibodies
    SMARCD1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily D, Member 1 (SMARCD1))
    Binding Specificity
    • 9
    • 9
    • 7
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 7-124
    Reactivity
    • 40
    • 24
    • 13
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 47
    • 1
    Rabbit
    Clonality
    • 47
    • 1
    Polyclonal
    Conjugate
    • 22
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SMARCD1 antibody is un-conjugated
    Application
    • 34
    • 24
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 protein (7-124AA)
    Isotype
    IgG
  • Application Notes
    Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    SMARCD1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily D, Member 1 (SMARCD1))
    Alternative Name
    SMARCD1 (SMARCD1 Products)
    Synonyms
    rsc6p antibody, baf60a antibody, cracd1 antibody, MGC69403 antibody, BAF60A antibody, CRACD1 antibody, Rsc6p antibody, wu:fa10h07 antibody, wu:fb82d01 antibody, wu:fi45f10 antibody, AA407987 antibody, Baf60a antibody, D15Kz1 antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 L homeolog antibody, SMARCD1 antibody, smarcd1 antibody, smarcd1.L antibody, Smarcd1 antibody
    Background

    Background: Involved in chromatin remodeling. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity). Has a strong influence on vitamin D-mediated transcriptional activity from an enhancer vitamin D receptor element (VDRE). May be a link between mammalian SWI-SNF-like chromatin remodeling complexes and the vitamin D receptor (VDR) heterodimer. Mediates critical interactions between nuclear receptors and the BRG1/SMARCA4 chromatin-remodeling complex for transactivation.

    Aliases: 60 kDa BRG-1/Brm-associated factor subunit A antibody, 60 kDa BRG1/Brm associated factor subunit A antibody, BAF60A antibody, BRG1 associated factor 60A antibody, BRG1-associated factor 60A antibody, Chromatin remodeling complex BAF60A subunit antibody, CRACD1 antibody, Mammalian chromatin remodeling complex BRG1 associated factor 60A antibody, Rsc6p antibody, SMARCD1 antibody, SMRD1 antibody, SMRD1_HUMAN antibody, SWI/SNF complex 60 kDa subunit A antibody, SWI/SNF complex 60 kDa subunit antibody, SWI/SNF related matrix associated actin dependent regulator of chromatin d1 antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 antibody, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 antibody, Swp73 like protein antibody

    UniProt
    Q96GM5
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