BBS2 antibody (C-Term)
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- Target See all BBS2 Antibodies
- BBS2 (Bardet-Biedl Syndrome 2 (BBS2))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This BBS2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Specificity
- BBS2 Antibody detects endogenous levels of total BBS2.
- Predicted Reactivity
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human BBS2, corresponding to a region within C-terminal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product BBS2 Primary Antibody
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anti-Bardet-Biedl Syndrome 2 (BBS2) (AA 1-96) antibody
BBS2 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 2 (BBS2) (AA 1-721) antibodyBBS2 Reactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 2 (BBS2) antibodyBBS2 Reactivity: Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 2 (BBS2) (AA 151-200) antibodyBBS2 Reactivity: Human, Dog, Horse, Rabbit, Zebrafish (Danio rerio), Cow, Guinea Pig, Bat, Monkey WB Host: Rabbit Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 2 (BBS2) (AA 315-364) antibodyBBS2 Reactivity: Human, Mouse, Dog, Horse, Rabbit, Zebrafish (Danio rerio), Cow, Bat, Chicken WB Host: Rabbit Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 2 (BBS2) (N-Term) antibodyBBS2 Reactivity: Human, Mouse, Rat, Dog, Horse, Rabbit, Zebrafish (Danio rerio), Cow, Guinea Pig WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- BBS2 (Bardet-Biedl Syndrome 2 (BBS2))
- Alternative Name
- BBS2 (BBS2 Products)
- Synonyms
- fb80a05 antibody, wu:fb80a05 antibody, DKFZp468B105 antibody, DKFZp469L0919 antibody, BBS antibody, 2410125H22Rik antibody, AI447581 antibody, Bardet-Biedl syndrome 2 antibody, bardet-biedl syndrome 2 antibody, Bardet-Biedl syndrome 2 (human) antibody, bbs2 antibody, BBS2 antibody, Bbs2 antibody
- Background
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Description: The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. Required for proper BBSome complex assembly and its ciliary localization.
Gene: BBS2
- Molecular Weight
- 80 kDa
- Gene ID
- 583
- UniProt
- Q9BXC9
- Pathways
- Hedgehog Signaling
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