BBS2 antibody (N-Term)

Catalog No. ABIN2788195

This Rabbit Polyclonal antibody specifically detects BBS2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Zebrafish (Danio rerio) and Guinea Pig.

Quick Overview for BBS2 antibody (N-Term) (ABIN2788195)

Target: BBS2 (Bardet-Biedl Syndrome 2 (BBS2))

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Zebrafish (Danio rerio), Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BBS2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BBS2 Antibody

Binding Specificity: N-Term

Purpose: BBS2 Antibody - N-terminal region

Sequence: GSDLFWTVTG DNVNSLALCD FDGDGKKELL VGSEDFDIRV FKEDEIVAEM

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against BBS2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human BBS2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59752-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for BBS2

Target: BBS2 (Bardet-Biedl Syndrome 2 (BBS2))

Alternative Name: BBS2

Background:

Background Information: This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by severe pigmentary retinopathy, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene forms a multiprotein BBSome complex with six other BBS proteins.

Gene Name: Bardet-Biedl syndrome 2

Alternative Symbols: BBS, RP74

Protein Name: Bardet-Biedl syndrome 2 protein

Molecular Weight: 80kDa

Gene ID: 583

NCBI Accession: NP_114091

UniProt: Q9BXC9

Pathways: Hedgehog Signaling