PPP1R11 antibody (AA 1-126)
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- Target See all PPP1R11 Antibodies
- PPP1R11 (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 11 (PPP1R11))
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Binding Specificity
- AA 1-126
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PPP1R11 antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC)
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human E3 ubiquitin-protein ligase PPP1R11 protein (1-126AA)
- Isotype
- IgG
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- Application Notes
- Recommended dilution: IHC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- PPP1R11 (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 11 (PPP1R11))
- Alternative Name
- PPP1R11 (PPP1R11 Products)
- Synonyms
- HCG-V antibody, HCGV antibody, IPP3 antibody, TCTE5 antibody, TCTEX5 antibody, 1500041B02Rik antibody, AV117883 antibody, Hcgv antibody, Tcte5 antibody, Tctex-5 antibody, Tctex5 antibody, wu:fj64e04 antibody, zgc:110245 antibody, protein phosphatase 1 regulatory inhibitor subunit 11 antibody, protein phosphatase 1, regulatory (inhibitor) subunit 11 antibody, PPP1R11 antibody, Ppp1r11 antibody, ppp1r11 antibody
- Background
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Background: Atypical E3 ubiquitin-protein ligase which ubiquitinates TLR2 at \\\'Lys-754\\\' leading to its degradation by the proteasome. Plays a role in regulating inflammatory cytokine release and gram-positive bacterial clearance by functioning, in part, through the ubiquitination and degradation of TLR2 (PubMed:27805901). Inhibitor of protein phosphatase 1 (PubMed:9843442).
Aliases: PPP1R11 antibody, HCGV antibody, TCTE5 antibody, E3 ubiquitin-protein ligase PPP1R11 antibody, EC 2.3.2.27 antibody, Hemochromatosis candidate gene V protein antibody, HCG V antibody, Protein phosphatase 1 regulatory subunit 11 antibody, Protein phosphatase inhibitor 3 antibody
- UniProt
- O60927
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