CD19 Protein (AA 20-292) (His tag)
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- Target See all CD19 Proteins
- CD19 (CD19 Molecule (CD19))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 20-292
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Origin
- Rhesus Monkey, Cynomolgus
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CD19 protein is labelled with His tag.
- Characteristics
- Cynomolgus / Rhesus macaque CD19 (20-292) Protein, His Tag
- Purity
- >90 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product CD19 Protein
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CD19 Molecule (CD19) (AA 20-291) protein (His tag,FITC)
CD19 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD19 Molecule (CD19) (AA 20-291) (Active) protein (His tag)CD19 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by reduced SDS-PAGE. Active
CD19 Molecule (CD19) (AA 20-291) (Active) protein (Fc Tag)CD19 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
CD19 Molecule (CD19) (AA 20-291) (Active) protein (Fc Tag,Biotin)CD19 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by reduced SDS-PAGE. Active
CD19 Molecule (CD19) (AA 21-291) protein (His tag)CD19 Origin: Rhesus Monkey, Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD19 Molecule (CD19) (AA 20-291) protein (His tag)CD19 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
CD19 Molecule (CD19) (AA 20-291) (Active) protein (His tag,AVI tag,Biotin)CD19 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
CD19 Molecule (CD19) (AA 19-287) protein (His tag)CD19 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Tris-Bis PAGE
CD19 Molecule (CD19) (AA 1-556) protein (GST tag)CD19 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
CD19 Molecule (CD19) (AA 98-187) protein (GST tag)CD19 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -20 °C
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- Target
- CD19 (CD19 Molecule (CD19))
- Alternative Name
- CD19 (CD19 Products)
- Synonyms
- B4 Protein, CVID3 Protein, AW495831 Protein, CD19 Protein, CD19 molecule Protein, CD19 antigen Protein, CD19 Protein, Cd19 Protein
- Background
- B-lymphocyte antigen CD19 is also known as CD19 (Cluster of Differentiation 19), is a single-pass type I membrane protein which contains two Ig-like C2-type (immunoglobulin-like) domains. CD19 is expressed on follicular dendritic cells and B cells. In fact, it is present on B cells from earliest recognizable B-lineage cells during development to B-cell blasts but is lost on maturation to plasma cells. It primarily acts as a B cell co-receptor in conjunction with CD21 and CD81. Upon activation, the cytoplasmic tail of CD19 becomes phosphorylated, which leads to binding by Src-family kinases and recruitment of PI-3 kinase. As on T cells, several surface molecules form the antigen receptor and form a complex on B lymphocytes. The (almost) B cell-specific CD19 phosphoglycoprotein is one of these molecules. The others are CD21 and CD81. These surface immunoglobulin (sIg)-associated molecules facilitate signal transduction. On living B cells, anti-immunoglobulin antibody mimicking exogenous antigen causes CD19 to bind to sIg and internalize with it. The reverse process has not been demonstrated, suggesting that formation of this receptor complex is antigen-induced. This molecular association has been confirmed by chemical studies. Mutations in CD19 are associated with severe immunodeficiency syndromes characterized by diminished antibody production. CD19 has been shown to interact with: CD81, CD82, Complement receptor 2, and VAV2.
- Molecular Weight
- 32.1 kDa
- NCBI Accession
- XP_001103043
- Pathways
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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