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P2RY12 antibody

P2RY12 Reactivity: Mouse, Rat WB, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7075321
  • Target See all P2RY12 Antibodies
    P2RY12 (Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12))
    Reactivity
    • 37
    • 25
    • 10
    • 7
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    Mouse, Rat
    Host
    • 39
    • 1
    Rabbit
    Clonality
    • 37
    • 3
    Polyclonal
    Conjugate
    • 17
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This P2RY12 antibody is un-conjugated
    Application
    • 34
    • 13
    • 13
    • 8
    • 7
    • 7
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Cross-Reactivity
    Rat
    Purification
    Affinity purification
    Immunogen
    KLH conjugated Synthetic peptide corresponding to Mouse P2Y12
    Top Product
    Discover our top product P2RY12 Primary Antibody
  • Application Notes
    WB (M,R) 1:250-1:500, IHC/IF (M,R) 1:1000-1:3000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS, pH 7.4, 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
  • Target
    P2RY12 (Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12))
    Alternative Name
    P2Y12 (P2RY12 Products)
    Synonyms
    2900079B22Rik antibody, 4921504D23Rik antibody, P2Y12 antibody, ADPG-R antibody, BDPLT8 antibody, HORK3 antibody, P2T(AC) antibody, P2Y(12)R antibody, P2Y(AC) antibody, P2Y(ADP) antibody, P2Y(cyc) antibody, SP1999 antibody, P2y12 antibody, purinergic receptor P2Y, G-protein coupled 12 antibody, purinergic receptor P2Y12 antibody, P2ry12 antibody, P2RY12 antibody
    Background
    The P2Y receptor family are G protein-coupled receptors which mediate the effects of extracellular nucleotides, primarily through the activation of phospholipase C. To some extent, the P2Y receptors can also activate potassium channels or, alternatively, inhibit adenylate cyclase and N-type calcium channels in response to extracellular nucleotides. Human platelets express two G protein-coupled nucleotide receptors, P2Y1 and P2Y12. P2Y12 is a receptor for ADP and ATP coupled to G-proteins that inhibit the adenylyl cyclase second messenger system. P2Y12 is an integral membrane protein involved in platelet aggregation. It is highly expressed in platelets, with lower levels in the brain, lung, appendix, pituitary and adrenal gland.
    Molecular Weight
    50 kDa
    Gene ID
    70839
    NCBI Accession
    NP_081847
    UniProt
    Q9CPV9
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